Price J C, Percarpio B, Murphy P W, Henderson R L
Otolaryngol Head Neck Surg (1979). 1979 Sep-Oct;87(5):614-23. doi: 10.1177/019459987908700514.
Malignant neoplasms of the trachea are rare lesions, of which adenoid cystic carcinoma constitutes 30%. A case of extensive tumor recurrent after primary radiotherapy is presented. Surgical resection and radioisotope implantation were impossible. A method was devised for placement of intraluminal iridium 192 by casting six small hollow plastic tubes to the outer circumference of a Silastic endotracheal tube. This was an easy, safe, and effective method of delivering radiation to the trachea while sparing other vital structures and organs. Excellent tumor response and palliation were achieved. The literature is reviewed and the problems in diagnosis of this tumor are discussed. A comprehensive plan for early diagnosis is presented. All current methods of treatment are discussed, and the need for aggressive surgical management is stressed.
气管恶性肿瘤是罕见病变,其中腺样囊性癌占30%。本文报告1例原发性放疗后广泛肿瘤复发的病例。手术切除和放射性同位素植入均无法进行。设计了一种方法,通过将6根小的中空塑料管铸型到硅橡胶气管导管的外周来放置腔内铱192。这是一种向气管输送辐射的简便、安全且有效的方法,同时可避免其他重要结构和器官受到辐射。取得了良好的肿瘤反应和姑息效果。本文回顾了相关文献并讨论了该肿瘤的诊断问题。提出了早期诊断的综合方案。讨论了所有当前的治疗方法,并强调了积极手术治疗的必要性。