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诊断测试在原发性高血压青少年中的应用。

Use of diagnostic tests in adolescents with essential hypertension.

作者信息

Yoon Esther Y, Cohn Lisa, Rocchini Albert, Kershaw David, Freed Gary, Ascione Frank, Clark Sarah

机构信息

Division of General Pediatrics, Child Health Evaluation and Research Unit, University of Michigan, Ann Harbor, USA.

出版信息

Arch Pediatr Adolesc Med. 2012 Sep;166(9):857-62. doi: 10.1001/archpediatrics.2012.1173.

Abstract

OBJECTIVE

To describe the use of diagnostic tests in adolescents with essential hypertension.

DESIGN

Longitudinal analysis of administrative claims data.

SETTING

Michigan Medicaid program during 2003 to 2008.

PARTICIPANTS

Adolescents with 3 or more years of Medicaid eligibility (≥ 11 months/y) who had a diagnosis of essential hypertension and 1 or more antihypertensive medication pharmacy claims.

MAIN OUTCOME MEASURES

We examined adolescents' echocardiogram use and compared it with electrocardiogram (EKG) and renal ultrasonography use. We examined timing of the 3 diagnostic tests in relation to the first pharmacy claim. We examined patient demographics and presence of obesity-related comorbidities.

RESULTS

During 2003 to 2008, there were 951 adolescents with essential hypertension who had antihypertensive pharmacy claims; 24% (226) had echocardiograms; 22% (207) had renal ultrasonography; and 50% (478) had EKGs. Males (odds ratio [OR], 1.53; 95% CI, 1.06-2.21), younger adolescents (OR, 1.69; 95% CI, 1.17-2.44), those who had EKGs (OR, 5.79; 95% CI, 4.02-8.36), and those who had renal ultrasonography (OR, 2.22; 95% CI, 1.54-3.20) were more likely to obtain echocardiograms compared with females, older adolescents, and adolescents who did not have EKGs or renal ultrasonography.

CONCLUSIONS

Guideline-recommended diagnostic tests-echocardiograms and renal ultrasonography-were equally poorly used by adolescents with essential hypertension. Sex and age differences exist in the use of echocardiograms by adolescents with essential hypertension. The decision and choice of diagnostic tests to evaluate adolescents with essential hypertension warrant further study to understand the underlying rationale for those decisions and to determine treatment effectiveness.

摘要

目的

描述诊断测试在原发性高血压青少年中的应用情况。

设计

对行政索赔数据进行纵向分析。

背景

2003年至2008年期间的密歇根医疗补助计划。

参与者

符合医疗补助资格3年或以上(≥11个月/年)、被诊断为原发性高血压且有1次或以上抗高血压药物药房索赔记录的青少年。

主要观察指标

我们研究了青少年超声心动图的使用情况,并将其与心电图(EKG)和肾脏超声检查的使用情况进行比较。我们研究了这三项诊断测试相对于首次药房索赔的时间安排。我们研究了患者的人口统计学特征以及肥胖相关合并症的存在情况。

结果

在2003年至2008年期间,有951名患有原发性高血压且有抗高血压药房索赔记录的青少年;24%(226名)进行了超声心动图检查;22%(207名)进行了肾脏超声检查;50%(478名)进行了心电图检查。与女性、年龄较大的青少年以及未进行心电图或肾脏超声检查的青少年相比,男性(优势比[OR],1.53;95%置信区间[CI],1.06 - 2.21)、年龄较小的青少年(OR,1.69;95% CI,1.17 - 2.44)、进行了心电图检查的青少年(OR,5.79;95% CI,4.02 - 8.36)以及进行了肾脏超声检查的青少年(OR,2.22;95% CI,1.54 - 3.20)更有可能进行超声心动图检查。

结论

原发性高血压青少年对指南推荐的诊断测试——超声心动图和肾脏超声检查——的使用同样不佳。原发性高血压青少年在超声心动图使用方面存在性别和年龄差异。评估原发性高血压青少年时诊断测试的决策和选择值得进一步研究,以了解这些决策的潜在依据并确定治疗效果。

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