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多个颈椎节段:颈椎前路椎间盘切除术后吞咽困难和发音困难的风险增加。

Multiple cervical levels: increased risk of dysphagia and dysphonia during anterior cervical discectomy.

机构信息

Physiologic Assessment Services, Teaneck, NJ, USA.

出版信息

J Neurosurg Anesthesiol. 2012 Oct;24(4):350-5. doi: 10.1097/ANA.0b013e3182622843.

DOI:10.1097/ANA.0b013e3182622843
PMID:22828154
Abstract

BACKGROUND

Anterior cervical discectomy (ACD) is widely used for symptomatic cervical spine pathologies. The most common complications associated with this type of surgery are dysphagia and dysphonia; however, the risk factors associated with them have not been adequately elucidated. The purpose of this study is to assess the incidence of self-reported dysphagia and dysphonia and the associated risk factors after ACD.

METHODS

This study used a retrospective chart review of 149 patients who underwent ACD at a tertiary care facility operating in the New York metropolitan area over a period of 2½ years. Charts for ACD patients were reviewed by 6 trained researchers. Incidence rates for self-reported dysphagia and dysphonia were calculated using 95% exact confidence intervals (CI). Risk factors such as age, sex, surgical hours, number of disc levels, airway class, American Society of Anesthesiologists class, fiberoptic intubation, and intubation difficulty were assessed using logistic regression.

RESULTS

The incidence of self-reported dysphagia was 12.1% (95% exact CI, 7.3%-18.4%); for dysphonia the self-reported incidence was 5.4% (95% exact CI, 2.3%-10.3%). Patients who underwent surgery at ≥4 cervical levels had a significant 4-fold increased risk (odds ratio=4; 95% CI, 1.1-13.8) of developing dysphonia and/or dysphagia compared with patients who underwent surgery at a single surgical level.

CONCLUSIONS

This study confirms previous findings that the risk of developing dysphagia and/or dysphonia increases with the number of surgical levels, with multiple cervical levels representing a significantly higher postoperative risk, as compared with surgery at 1 level.

摘要

背景

颈椎前路椎间盘切除术(ACD)广泛应用于治疗有症状的颈椎病变。该手术最常见的并发症为吞咽困难和声音嘶哑;但与之相关的危险因素尚未得到充分阐明。本研究旨在评估 ACD 术后报告的吞咽困难和声音嘶哑的发生率以及相关的危险因素。

方法

本研究对在纽约都会区一家三级医疗机构接受 ACD 的 149 例患者进行了回顾性图表审查,时间跨度为 2 年半。由 6 名经过培训的研究人员对 ACD 患者的图表进行了审查。使用 95%精确置信区间(CI)计算报告的吞咽困难和声音嘶哑的发生率。使用逻辑回归评估年龄、性别、手术时间、椎间盘水平数、气道分级、美国麻醉医师协会分级、纤维光学插管和插管难度等危险因素。

结果

报告的吞咽困难发生率为 12.1%(95%精确 CI,7.3%-18.4%);声音嘶哑的报告发生率为 5.4%(95%精确 CI,2.3%-10.3%)。与单一手术水平相比,接受≥4 个颈椎水平手术的患者发生声音嘶哑和/或吞咽困难的风险显著增加 4 倍(优势比=4;95%CI,1.1-13.8)。

结论

本研究证实了先前的发现,即吞咽困难和/或声音嘶哑的风险随手术水平的增加而增加,与单一手术水平相比,多个颈椎水平代表着更高的术后风险。

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