Department of Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Diabetes Care. 2012 Oct;35(10):2018-20. doi: 10.2337/dc12-0204. Epub 2012 Jul 24.
Limited information is available regarding the metabolic effects of high altitude trekking in patients with type 2 diabetes.
Thirteen individuals with type 2 diabetes took part in a 12-day expedition to the summit of Mount Toubkal (altitude, 4,167 m), Morocco, after 6 months of exercise training. Energy expenditure, body weight, blood glucose, fasting insulin, lipids, and HbA(1c) were assessed.
Training reduced fasting glucose (-0.7 ± 0.9 mmol/L, P = 0.026) and increased exercise capacity (+0.3 ± 0.3 W/kg, P = 0.005). High altitude trekking decreased fasting insulin concentrations (-3.8 ± 3.2 μU/L, P = 0.04), total cholesterol (-0.7 ± 0.8 mmol/L, P = 0.008), and LDL cholesterol (-0.5 ± 0.6 mmol/L, P = 0.007).
High altitude trekking preceded by exercise training is feasible for patients with type 2 diabetes. It improves blood glucose, lipids, and fasting insulin concentrations, while glucose control is maintained.
关于 2 型糖尿病患者在高海拔地区徒步旅行的代谢影响,相关信息有限。
13 名 2 型糖尿病患者在经过 6 个月的运动训练后,参加了为期 12 天的摩洛哥图卜卡勒山(海拔 4167 米)登顶探险活动。评估了能量消耗、体重、血糖、空腹胰岛素、血脂和 HbA1c。
训练降低了空腹血糖(-0.7±0.9mmol/L,P=0.026)并增加了运动能力(+0.3±0.3W/kg,P=0.005)。高原徒步旅行降低了空腹胰岛素浓度(-3.8±3.2μU/L,P=0.04)、总胆固醇(-0.7±0.8mmol/L,P=0.008)和 LDL 胆固醇(-0.5±0.6mmol/L,P=0.007)。
在运动训练之前进行高原徒步旅行对于 2 型糖尿病患者是可行的。它可以改善血糖、血脂和空腹胰岛素浓度,同时保持血糖控制。