Saadia Aiza, Mubarik Azher, Zubair Alia, Jamal Shahid, Zafar Ambreen
Department of Pathology, Army Medical College, Rawalpindi, Pakistan.
J Ayub Med Coll Abbottabad. 2011 Jan-Mar;23(1):129-31.
Abnormal uterine bleeding is one of the most frequent problems in life of an adult female. Uterine curettage or biopsy remains a preferred sampling procedure for diagnosis of the endometrial pathology. The objective of this study was to compare the sensitivity, specificity, positive and negative predictive value of endometrial curettage.
This validation study was carried out at the Department of Histopathology, Army Medical College Rawalpindi in collaboration with Military Hospital, Rawalpindi from January to December 2010. The study included 50 curettage and subsequent hysterectomy specimen of the same patients. Non-probability sampling technique was used to divide patients into two groups with 50 patients in each group. One group was of endometrial curettage having endometrial pathology (group A). Second group was of subsequent hysterectomy specimen of the same patients (group B).
Endometrial curettage was found most accurate in diagnosing endometrial carcinoma. Sensitivity of endometrial curettage was found to be 33% whereas specificity and positive predictive value was found to be 100% each. Negative predictive value was found to be 93.1%.
Endometrial biopsy is a sensitive and a specific test in and is accurate in diagnosing endometrial pathology. It is found most accurate in diagnosing endometrial carcinoma.
异常子宫出血是成年女性生活中最常见的问题之一。刮宫术或活检仍然是诊断子宫内膜病变的首选采样方法。本研究的目的是比较刮宫术的敏感性、特异性、阳性预测值和阴性预测值。
本验证性研究于2010年1月至12月在拉瓦尔品第陆军医学院组织病理学系与拉瓦尔品第军事医院合作开展。该研究纳入了50例同一患者的刮宫标本及随后的子宫切除标本。采用非概率抽样技术将患者分为两组，每组50例。一组为有子宫内膜病变的刮宫标本（A组）。第二组为同一患者随后的子宫切除标本（B组）。
发现刮宫术在诊断子宫内膜癌方面最为准确。刮宫术的敏感性为33%，而特异性和阳性预测值均为100%。阴性预测值为93.1%。
子宫内膜活检是一种敏感且特异的检查，在诊断子宫内膜病变方面准确。在诊断子宫内膜癌方面最为准确。
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