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心肌细胞肌原纤维变性在法医学病理学中的诊断意义

Diagnostic significance of myofibrillar degeneration of cardiocytes in forensic pathology.

作者信息

Oehmichen M, Pedal I, Hohmann P

机构信息

Institute of Forensic Medicine, University of Lübeck, F.R.G.

出版信息

Forensic Sci Int. 1990 Dec;48(2):163-73. doi: 10.1016/0379-0738(90)90109-c.

DOI:10.1016/0379-0738(90)90109-c
PMID:2283139
Abstract

The incidence of myofibrillar degeneration (MFD) was studied in the following different forensic-pathological diagnostic groups of 25 cases each: acute morphine intoxication, acute carbon monoxide intoxication, hanging, strangulation by hand/ligature, drowning, acute hemorrhagic shock, lethal acute brain injury, explainable death of babies or infants and sudden infant death syndrome, together with 18 cases of intoxication with various drugs. The MFD was demonstrated by the Luxol-fast-blue reaction, with two types of phenomena being differentiated, namely cross-band lesions and diffuse staining. All diagnostic groups included cases of MFD of differing degrees. Cross-band lesions were observed in practically all cases of hanging, strangulation and acute hemorrhagic shock. Diffuse stain was noted particularly in cases of drowning and acute brain injury. The diagnostic significance is discussed.

摘要

在以下不同的法医病理学诊断组中研究了肌原纤维变性(MFD)的发生率,每组25例:急性吗啡中毒、急性一氧化碳中毒、绞刑、手/绳索勒颈、溺水、急性失血性休克、致死性急性脑损伤、婴儿或幼儿可解释性死亡以及婴儿猝死综合征,还有18例各种药物中毒。通过Luxol固蓝反应证实了MFD,区分出两种现象,即交叉带病变和弥漫性染色。所有诊断组都包括不同程度MFD的病例。在几乎所有绞刑、勒颈和急性失血性休克病例中都观察到交叉带病变。弥漫性染色尤其见于溺水和急性脑损伤病例。讨论了其诊断意义。

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