Elliott Steve, Leishman Barbara
Department of Hematology, Amgen, Inc., One Amgen Center, Thousand Oaks, CA 91320, USA.
Bioanalysis. 2012 Jul;4(13):1681-90. doi: 10.4155/bio.12.137.
The misuse of medicines for performance enhancement in sport (doping) is not approved by regulatory agencies, and is illegal in many countries. In addition to the 'traditional' doping agents such as steroids, β-blockers and blood transfusions, the list of agents and techniques used in doping is increasing and now includes newer medicines such as erythropoiesis-stimulating agents and growth hormones. Innovative new medicines are of particular interest as would-be dopers may believe them to be undetectable by current methods. Close collaboration between the biopharmaceutical industry and anti-doping agencies such as the World Anti-Doping Agency is critical to a successful anti-doping strategy. Industry is ideally placed to identify the doping potential of new medicines at early stages and to support early development of detection assays. A strong, united front between the biopharmaceutical industry and anti-doping agencies is essential to counter the misuse of medicines for performance enhancement, as well as to promote fair play and clean sport.
在体育运动中滥用药物以提高成绩(使用兴奋剂)未得到监管机构的批准,并且在许多国家都是非法的。除了类固醇、β受体阻滞剂和输血等“传统”兴奋剂外,使用兴奋剂的药物和技术清单正在增加,现在还包括促红细胞生成素和生长激素等新型药物。创新的新药尤其令人关注,因为潜在的兴奋剂使用者可能认为它们目前的检测方法无法检测到。生物制药行业与世界反兴奋剂机构等反兴奋剂机构之间的密切合作对于成功的反兴奋剂战略至关重要。行业处于理想位置,能够在早期阶段识别新药的兴奋剂潜力,并支持检测方法的早期开发。生物制药行业和反兴奋剂机构之间形成强大、统一的阵线对于打击滥用药物以提高成绩的行为、促进公平竞争和纯净运动至关重要。