Department of Psychiatry and Psychotherapy, University Hospital, Zürich, Switzerland. hanspeter.moergeli @ usz.ch
Psychother Psychosom. 2012;81(5):305-11. doi: 10.1159/000330887. Epub 2012 Jul 20.
It is largely unknown how quality of life (QoL) changes following accidental injuries. Equally, the mechanisms underlying such changes have not yet been identified in detail. This study of injured accident survivors aimed to: (1) detect a model of change which best explains the observed course of QoL, and (2) identify potential predictor variables.
323 injured accident survivors were interviewed within 2 weeks of the trauma, and followed up at 6 and 12 months. Latent trajectory modeling was used to analyze the fit of three potential trajectories regarding the observed course of general QoL as measured by the Questions on Life Satisfaction questionnaire.
The trajectory model adopting a negative square-root change fitted the observed data best, meaning that shortly after the accident, general QoL decreased strongly with diminishing negative changes occurring later on. Early and prolonged QoL impairment was largely attributable to the initial level of posttraumatic stress as measured by the Clinician-Administered PTSD Scale. To a lesser extent, depressive symptoms also predicted change in subjective QoL, while injury severity showed no direct effect; rather, its impact on QoL was mediated by initial posttraumatic stress. By contrast, reduced occupational functioning was attributable to injury severity rather than psychopathology.
When treating injured accident survivors, clinicians should consider symptoms of posttraumatic stress and comorbid depression in order to prevent or mitigate negative changes in QoL.
人们对于意外伤害后生活质量(QoL)的变化知之甚少。同样,这些变化背后的机制也尚未详细确定。本研究旨在调查意外伤害幸存者:(1)发现最能解释 QoL 观察到的变化模式,以及(2)确定潜在的预测变量。
323 名意外伤害幸存者在创伤后 2 周内接受访谈,并在 6 个月和 12 个月时进行随访。使用潜在轨迹建模来分析三种潜在轨迹在通过生活满意度问卷测量的一般 QoL 的观察到的变化过程中的拟合度。
采用负平方根变化的轨迹模型最适合观察数据,这意味着在事故发生后不久,一般 QoL 会强烈下降,随后负面变化逐渐减少。早期和长期的 QoL 损害主要归因于创伤后应激障碍量表测量的初始创伤后应激水平。在较小程度上,抑郁症状也预测了主观 QoL 的变化,而伤害严重程度没有直接影响;相反,它对 QoL 的影响是通过初始创伤后应激介导的。相比之下,职业功能的降低归因于伤害严重程度而不是精神病理学。
在治疗意外伤害幸存者时,临床医生应考虑创伤后应激和共病抑郁的症状,以预防或减轻 QoL 的负面变化。