Melville Laboratory for Polymer Synthesis, Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK.
Chem Commun (Camb). 2012 Sep 11;48(70):8757-9. doi: 10.1039/c2cc34016j. Epub 2012 Jul 26.
Core-shell polymeric microspheres with a cleavable shell were prepared in water using cucurbit[8]uril to bring together functional polymeric microspheres and functional polymers. This supramolecular approach was employed to switch the cytotoxicity of the polymeric microspheres, leading to potential applications in the eradication of cancer cells.
采用葫芦[8]脲将功能性聚合微球和功能性聚合物聚集在一起，在水中制备了具有可裂解壳的核壳型聚合微球。这种超分子方法被用来改变聚合微球的细胞毒性，从而有可能应用于癌细胞的消除。
