• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

术后结肠造口术患者使用缓泻剂的随机对照试验。

Randomized controlled trial of laxative use in postcolostomy surgery patients.

机构信息

Stomal Therapy Nursing, Stomal Therapy Department, Prince of Wales Hospital, Sydney, New South Wales, Australia.

出版信息

J Wound Ostomy Continence Nurs. 2012 Sep-Oct;39(5):524-8. doi: 10.1097/WON.0b013e3182648cc9.

DOI:10.1097/WON.0b013e3182648cc9
PMID:22832811
Abstract

PURPOSE

We compared a standardized postoperative laxative protocol to laxatives provided on an ad hoc basis by the surgical team.

SUBJECTS AND SETTING

Forty-five patients who underwent colostomy surgery participated in the study. The research setting was 2 acute care facilities in south-eastern Sydney, New South Wales, Australia.

METHODS

A randomized controlled trial was conducted. The intervention group (n 5 19) received a standardized laxative protocol postsurgery. Two types of laxatives were selected for first-line treatment: sterculia and frangula bark (Normacol Plus), a bulking agent and stimulant; and liquid paraffin (Agarol), a stool softener. An iso-osmotic polyethylene glycol macrogel (Movicol) was chosen as second-line treatment. The comparison group (n = 26) received laxative intervention(s) as preferred by the surgical team. Constipation, measured as fecal loading on plain abdominal film, stomal therapy nurse activity, patient comfort, and length of hospital stay were compared between intervention and control groups.

RESULTS

The presence of fecal loading favored the intervention group (1 episode in the treatment group vs 7 episodes in the comparison group; χ5 = 3.8; P = .05). This finding suggests that the laxative protocol given to the treatment group was more likely to prevent fecal loading/constipation when compared to the ad hoc laxative group. Stomal therapy nurse activity in terms of the number of empty bag changes was significantly higher in the comparison group (F 5 4.8; P 5 .03).

CONCLUSION

The findings of this study support the benefits of a standardized laxative protocol for prevention of constipation. Data collection was discontinued after 3 years due to a contamination effect developing, because our surgeons observed the utility of the laxative protocol and incorporated it into their routine practice. Further experimental research is needed to explore the best constipation prevention approaches for postcolostomy surgery patients.

摘要

目的

我们比较了标准化术后通便方案与手术团队按需提供的通便剂。

对象和设置

45 名接受结肠造口术的患者参与了这项研究。研究地点是澳大利亚新南威尔士州东南部悉尼的 2 个急性护理机构。

方法

进行了一项随机对照试验。干预组(n=19)术后接受标准化通便方案。选择了两种类型的通便剂作为一线治疗:洋槐树胶和鼠李皮(Normacol Plus),一种膨松剂和刺激剂;以及液体石蜡(Agarol),一种大便软化剂。选择等渗聚乙二醇大凝胶(Movicol)作为二线治疗。对照组(n=26)接受手术团队首选的通便干预措施。比较干预组和对照组之间的便秘情况(通过腹部平片上的粪便负荷来衡量)、造口治疗护士的活动、患者舒适度和住院时间。

结果

粪便负荷情况有利于干预组(治疗组 1 例,对照组 7 例;χ5=3.8;P=0.05)。这一发现表明,与按需使用通便剂的对照组相比,给予治疗组的通便方案更有可能预防粪便负荷/便秘。对照组造口治疗护士更换空袋的次数明显更高(F5=4.8;P=0.03)。

结论

这项研究的结果支持使用标准化通便方案预防便秘的益处。由于我们的外科医生观察到通便方案的实用性并将其纳入常规实践,因此在 3 年后因出现污染效应而停止了数据收集。需要进一步的实验研究来探索预防结肠造口术后患者便秘的最佳方法。

相似文献

1
Randomized controlled trial of laxative use in postcolostomy surgery patients.术后结肠造口术患者使用缓泻剂的随机对照试验。
J Wound Ostomy Continence Nurs. 2012 Sep-Oct;39(5):524-8. doi: 10.1097/WON.0b013e3182648cc9.
2
Effectiveness of senna vs polyethylene glycol as laxative therapy in children with constipation related to anorectal malformation.番泻叶与聚乙二醇作为泻药疗法对肛门直肠畸形相关便秘儿童的疗效。
J Pediatr Surg. 2017 Jan;52(1):84-88. doi: 10.1016/j.jpedsurg.2016.10.021. Epub 2016 Oct 27.
3
Polyethylene glycol: a game-changer laxative for children.聚乙二醇:儿童通便的变革性药物。
J Pediatr Gastroenterol Nutr. 2013 Aug;57(2):134-40. doi: 10.1097/MPG.0b013e318296404a.
4
A randomized controlled trial of enemas in combination with oral laxative therapy for children with chronic constipation.灌肠联合口服泻药治疗儿童慢性便秘的随机对照试验
Clin Gastroenterol Hepatol. 2009 Oct;7(10):1069-74. doi: 10.1016/j.cgh.2009.06.018. Epub 2009 Jul 1.
5
Biofeedback, biofeedback plus fiber laxative, and biofeedback plus osmotic laxative regimens to treat constipation in patients with pelvic floor dyssynergia: A randomized controlled trial.生物反馈、生物反馈联合纤维性泻药以及生物反馈联合渗透性泻药治疗盆底失协调患者便秘的随机对照试验。
Indian J Gastroenterol. 2022 Apr;41(2):160-168. doi: 10.1007/s12664-021-01189-1. Epub 2022 Mar 2.
6
Disimpaction of children with severe constipation in 3-4 days in a suburban clinic using polyethylene glycol with electrolytes and sodium picosulphate.在一家郊区诊所,使用聚乙二醇电解质散和匹可硫酸钠,在3至4天内解除重度便秘儿童的粪块嵌塞。
J Paediatr Child Health. 2015 Dec;51(12):1195-8. doi: 10.1111/jpc.12939. Epub 2015 Jun 8.
7
Laxative management in ambulatory cancer patients on opioid therapy: a prospective, open-label investigation of polyethylene glycol, sodium picosulphate and lactulose.门诊癌症患者阿片类药物治疗时的泻药管理:聚乙二醇、磷酸钠盐和乳果糖的前瞻性、开放标签研究。
Eur J Cancer Care (Engl). 2012 Jan;21(1):131-40. doi: 10.1111/j.1365-2354.2011.01286.x. Epub 2011 Aug 31.
8
A comparison of polyethylene glycol laxative and placebo for relief of constipation from constipating medications.聚乙二醇泻药与安慰剂用于缓解便秘性药物所致便秘的比较。
South Med J. 2007 Nov;100(11):1085-90. doi: 10.1097/SMJ.0b013e318157ec8f.
9
Inpatient use of laxatives during opioid administration in children with sickle cell disease.住院患儿在使用阿片类药物期间使用泻药。
Pediatr Blood Cancer. 2010 Apr;54(4):559-62. doi: 10.1002/pbc.22395.
10
Efficacy and tolerability of peg-only laxative on faecal impaction and chronic constipation in children. A controlled double blind randomized study vs a standard peg-electrolyte laxative.PEG 制剂在儿童粪嵌塞和慢性便秘中的疗效和耐受性。与标准 PEG-电解质泻药的对照双盲随机研究。
BMC Pediatr. 2012 Nov 15;12:178. doi: 10.1186/1471-2431-12-178.

引用本文的文献

1
Mismatch of populations between randomised controlled trials of perioperative interventions in major abdominal surgery and current clinical practice.大型腹部手术围手术期干预随机对照试验与当前临床实践中人群的不匹配。
Perioper Med (Lond). 2023 Nov 16;12(1):60. doi: 10.1186/s13741-023-00344-w.