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急性生理学与慢性健康状况评分系统 II 有助于预测结直肠来源的继发性腹膜炎患者再次剖腹手术的需求。

The Acute Physiology and Chronic Health Evaluation II score is helpful in predicting the need of relaparotomies in patients with secondary peritonitis of colorectal origin.

机构信息

Department of Surgery, University Hospital Basel, Switzerland.

出版信息

Swiss Med Wkly. 2012 Jul 25;142:w13640. doi: 10.4414/smw.2012.13640. eCollection 2012.

DOI:10.4414/smw.2012.13640
PMID:22832947
Abstract

BACKGROUND

Secondary peritonitis of colorectal origin has considerable morbidity and mortality. Relaparotomies are frequently necessary in the course of the disease. The objective of this study was to evaluate several scores in terms of their predictive value, i.e. whether Mannheim Peritonitis Index (MPI), Acute Physiology And Chronic Health Evaluation (APACHE) II, or Colorectal Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (CR-POSSUM) scores can predict relaparotomies.

METHODS

Charts of 147 patients treated for secondary peritonitis of colorectal origin were retrospectively reviewed, MPI, APACHE II, and CR-POSSUM scores were calculated, and groups of patients with or without relaparotomies were compared.

RESULTS

Thirty-four percent of patients underwent one or more relaparotomies. Patients with relaparotomies showed a significantly higher APACHE II score than patients without relaparotomies (p = 0.004). MPI (p = 0.072) and CR-POSSUM score (p = 0.319) did not differ between the two groups. A high APACHE II score was also significantly associated with the need for a relaparotomy on demand (p <0.001), and for the combined outcome parameter relaparotomy and/or an interventional drainage (p = 0.046). Both other scores were not predictive for these outcomes. Overall in-hospital mortality was 21.8%. All three scores investigated were predictive for mortality. Sensitivity was 62.5%, 78.1%, and 75.0% for MPI, APACHE II score, and CR-POSSUM score, respectively.

CONCLUSION

The Acute Physiology And Chronic Health Evaluation II score might be helpful in predicting the need for relaparotomies in patients with secondary peritonitis of colorectal origin.

摘要

背景

结直肠来源的继发性腹膜炎具有相当高的发病率和死亡率。在疾病的过程中经常需要再次剖腹手术。本研究的目的是评估几种评分的预测价值,即曼海姆腹膜炎指数(MPI)、急性生理学和慢性健康评估(APACHE)II 或结直肠生理和手术严重程度评分用于死亡率和发病率枚举(CR-POSSUM)评分是否可以预测再次剖腹手术。

方法

回顾性分析了 147 例接受结直肠来源继发性腹膜炎治疗的患者的病历,计算了 MPI、APACHE II 和 CR-POSSUM 评分,并比较了有或没有再次剖腹手术的患者组。

结果

34%的患者接受了一次或多次再次剖腹手术。有再次剖腹手术的患者的 APACHE II 评分明显高于没有再次剖腹手术的患者(p=0.004)。MPI(p=0.072)和 CR-POSSUM 评分(p=0.319)在两组之间无差异。高 APACHE II 评分也与再次剖腹手术的需求显著相关(p<0.001),以及联合结局参数再次剖腹手术和/或介入引流(p=0.046)。其他两个评分均不能预测这些结果。总住院死亡率为 21.8%。所研究的三个评分均预测死亡率。MPI、APACHE II 评分和 CR-POSSUM 评分的敏感性分别为 62.5%、78.1%和 75.0%。

结论

急性生理学和慢性健康评估 II 评分可能有助于预测结直肠来源继发性腹膜炎患者再次剖腹手术的需求。

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