Demmel N, Muth G, Maag K, Osterholzer G
1. Chirurgische Abteilung, Städtisches Krankenhaus München-Neuperlach.
Langenbecks Arch Chir. 1994;379(6):347-52. doi: 10.1007/BF00191581.
Scoring systems are mandatory to quantify the severity of abdominal sepsis on the basis of objective criteria. The Mannheim Peritonitis Index (MPI) is a disease-specific score based on easy to handle clinical parameters. APACHE II is a large-scale general scoring system with acute physiological and chronic health parameters. To evaluate the prognostic value of both systems 108 patients with severe abdominal infection managed by open treatment entered a prospective study. 32 patients (29.6%) died, 23 of them due to sepsis and 9 from other causes. Both MPI and APACHE II scores correlated closely with mortality, with three and two significantly different classes, respectively. Statistical validation showed a sensitivity of 93% and a specificity of 16% for MPI, and 89% and 25% for the APACHE II. ROC curves were nearly parallel for both scores. In conclusion there was no significant difference in prognostic value between the scoring systems.
评分系统对于根据客观标准量化腹部脓毒症的严重程度至关重要。曼海姆腹膜炎指数(MPI)是基于易于处理的临床参数的疾病特异性评分。急性生理与慢性健康状况评估系统(APACHE II)是一个包含急性生理和慢性健康参数的大规模通用评分系统。为评估这两种系统的预后价值,108例接受开放治疗的严重腹部感染患者进入一项前瞻性研究。32例患者(29.6%)死亡,其中23例死于脓毒症,9例死于其他原因。MPI和APACHE II评分均与死亡率密切相关,分别有三个和两个显著不同的类别。统计验证显示,MPI的敏感性为93%,特异性为16%;APACHE II的敏感性为89%,特异性为25%。两种评分的ROC曲线几乎平行。总之,评分系统之间的预后价值没有显著差异。