The Wolfson Brain Imaging Centre, Box 65 Addenbrooke's Hospital, CB2 0QQ, Cambridge, United Kingdom.
Org Biomol Chem. 2012 Sep 14;10(34):6980-6. doi: 10.1039/c2ob25802a. Epub 2012 Jul 26.
A rapid and efficient protocol to afford the title compound 2-[(18)F]-fluoro-2,2-difluoroethyl tosylate ([(18)F]7b) is described. Starting from [(18)F]fluoride ion, labelling reagent 7b was obtained in good yields and a high specific radioactivity. Compound ([(18)F]7b) was then used to synthesise a prospective radiotracer for PET-imaging in dementia.
描述了一种快速有效的方法，以获得标题化合物 2-[(18)F]-氟-2,2-二氟乙基对甲苯磺酸酯([(18)F]7b)。从[(18)F]氟离子开始，标记试剂 7b 以良好的产率和高比放射性得到。然后将化合物([(18)F]7b)用于合成用于痴呆症 PET 成像的潜在放射性示踪剂。
Zotero 插件