Zeng Ming, Han Liang-Fu
Department of Radiation Oncology, Zangmeister Cancer Center, Columbus, OH 43219, USA.
Chin J Cancer. 2012 Oct;31(10):471-5. doi: 10.5732/cjc.012.10011. Epub 2012 Jul 26.
The developments of medicine always follow innovations in science and technology. In the past decade, such innovations have made cancer-related targeted therapies possible. In general, the term "targeted therapy" has been used in reference to cellular and molecular level oriented therapies. However, improvements in the delivery and planning of traditional radiation therapy have also provided cancer patients more options for "targeted" treatment, notably stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). In this review, the progress and controversies of SRS and SBRT are discussed to show the role of stereotactic radiation therapy in the ever evolving multidisciplinary care of cancer patients.
医学的发展总是紧跟科学技术的创新步伐。在过去十年中,此类创新已使癌症相关的靶向治疗成为可能。一般而言,“靶向治疗”一词已用于指代面向细胞和分子水平的治疗方法。然而,传统放射治疗在输送和规划方面的改进也为癌症患者提供了更多“靶向”治疗选择,尤其是立体定向放射外科手术(SRS)和立体定向体部放射治疗(SBRT)。在本综述中,将讨论SRS和SBRT的进展与争议,以展示立体定向放射治疗在不断发展的癌症患者多学科护理中的作用。