• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

立体定向放射外科:一种癌症“靶向”治疗方法。

Stereotactic radiosurgery: a "targeted" therapy for cancer.

作者信息

Zeng Ming, Han Liang-Fu

机构信息

Department of Radiation Oncology, Zangmeister Cancer Center, Columbus, OH 43219, USA.

出版信息

Chin J Cancer. 2012 Oct;31(10):471-5. doi: 10.5732/cjc.012.10011. Epub 2012 Jul 26.

DOI:10.5732/cjc.012.10011
PMID:22835385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3777454/
Abstract

The developments of medicine always follow innovations in science and technology. In the past decade, such innovations have made cancer-related targeted therapies possible. In general, the term "targeted therapy" has been used in reference to cellular and molecular level oriented therapies. However, improvements in the delivery and planning of traditional radiation therapy have also provided cancer patients more options for "targeted" treatment, notably stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). In this review, the progress and controversies of SRS and SBRT are discussed to show the role of stereotactic radiation therapy in the ever evolving multidisciplinary care of cancer patients.

摘要

医学的发展总是紧跟科学技术的创新步伐。在过去十年中,此类创新已使癌症相关的靶向治疗成为可能。一般而言,“靶向治疗”一词已用于指代面向细胞和分子水平的治疗方法。然而,传统放射治疗在输送和规划方面的改进也为癌症患者提供了更多“靶向”治疗选择,尤其是立体定向放射外科手术(SRS)和立体定向体部放射治疗(SBRT)。在本综述中,将讨论SRS和SBRT的进展与争议,以展示立体定向放射治疗在不断发展的癌症患者多学科护理中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b65/3777454/f30fefab63b3/cjc-31-10-471-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b65/3777454/e3e2f219f32c/cjc-31-10-471-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b65/3777454/6b675e7eb87f/cjc-31-10-471-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b65/3777454/8af5a810129d/cjc-31-10-471-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b65/3777454/f30fefab63b3/cjc-31-10-471-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b65/3777454/e3e2f219f32c/cjc-31-10-471-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b65/3777454/6b675e7eb87f/cjc-31-10-471-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b65/3777454/8af5a810129d/cjc-31-10-471-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b65/3777454/f30fefab63b3/cjc-31-10-471-g004.jpg

相似文献

1
Stereotactic radiosurgery: a "targeted" therapy for cancer.立体定向放射外科:一种癌症“靶向”治疗方法。
Chin J Cancer. 2012 Oct;31(10):471-5. doi: 10.5732/cjc.012.10011. Epub 2012 Jul 26.
2
Principles and Applications of Stereotactic Radiosurgery and Stereotactic Body Radiation Therapy.立体定向放射外科和立体定向体部放射治疗的原则与应用。
Hematol Oncol Clin North Am. 2019 Dec;33(6):977-987. doi: 10.1016/j.hoc.2019.08.007. Epub 2019 Sep 27.
3
Efficacy of extracranial stereotactic body radiation therapy (SBRT) added to standard treatment in patients with solid tumors (breast, prostate and non-small cell lung cancer) with up to 3 bone-only metastases: study protocol for a randomised phase III trial (STEREO-OS).立体定向颅外放射治疗(SBRT)联合标准治疗在不超过 3 处仅有骨转移的实体瘤(乳腺癌、前列腺癌和非小细胞肺癌)患者中的疗效:一项随机 III 期试验(STEREO-OS)的研究方案。
BMC Cancer. 2021 Feb 4;21(1):117. doi: 10.1186/s12885-021-07828-2.
4
Progress and prospects of flattening filter free beam technology in radiosurgery and stereotactic body radiotherapy.无滤过板射束技术在放射外科和立体定向体部放疗中的进展与展望。
Crit Rev Oncol Hematol. 2021 Jul;163:103396. doi: 10.1016/j.critrevonc.2021.103396. Epub 2021 Jun 17.
5
Best of the Radiosurgery Society® Scientific Meeting 2014: stereotactic radiosurgery/stereotactic body radiotherapy treatment of extracranial and intracranial lesions.2014年放射外科学会®科学会议精华:立体定向放射外科/立体定向体部放射治疗颅外和颅内病变
Future Oncol. 2014 Dec;10(15):2307-10. doi: 10.2217/fon.14.168.
6
Stereotactic body radiotherapy treatment of extracranial metastases.立体定向体部放疗治疗颅外转移瘤。
Nat Rev Clin Oncol. 2012 Nov;9(11):654-65. doi: 10.1038/nrclinonc.2012.166. Epub 2012 Sep 25.
7
Stereotactic Radiosurgery and Stereotactic Body Radiotherapy in the Management of Oligometastatic Disease.立体定向放射外科和立体定向体部放射治疗在寡转移疾病治疗中的应用。
Clin Oncol (R Coll Radiol). 2020 Nov;32(11):713-727. doi: 10.1016/j.clon.2020.06.018. Epub 2020 Jul 24.
8
Assessment of Monte Carlo algorithm for compliance with RTOG 0915 dosimetric criteria in peripheral lung cancer patients treated with stereotactic body radiotherapy.评估蒙特卡罗算法在接受立体定向体部放射治疗的周围型肺癌患者中符合 RTOG 0915 剂量学标准的应用。
J Appl Clin Med Phys. 2016 May 8;17(3):277-293. doi: 10.1120/jacmp.v17i3.6077.
9
Stereotactic body radiation therapy: a novel treatment modality.立体定向体部放射治疗:一种新的治疗方式。
Nat Rev Clin Oncol. 2010 Jan;7(1):44-54. doi: 10.1038/nrclinonc.2009.188. Epub 2009 Dec 8.
10
Outcomes of stereotactic body radiotherapy (SBRT) treatment of multiple synchronous and recurrent lung nodules.立体定向体部放疗(SBRT)治疗多发同步及复发性肺结节的疗效
Radiat Oncol. 2015 Feb 18;10:43. doi: 10.1186/s13014-015-0340-9.

引用本文的文献

1
The Role of CyberKnife Stereotactic Radiosurgery in Recurrent Cranial Medulloblastomas across Pediatric and Adult Populations.射波刀立体定向放射外科在儿童和成人复发性颅髓母细胞瘤中的作用
J Clin Med. 2024 Jun 19;13(12):3592. doi: 10.3390/jcm13123592.

本文引用的文献

1
The evolution of phase I trials in cancer medicine: a critical review of the last decade.癌症医学中I期试验的演变:对过去十年的批判性综述。
Chin J Cancer. 2011 Dec;30(12):815-20. doi: 10.5732/cjc.011.10133. Epub 2011 Nov 4.
2
Stereotactic body radiotherapy for prostate cancer: current results of a phase II trial.
Front Radiat Ther Oncol. 2011;43:428-437. doi: 10.1159/000322507. Epub 2011 May 20.
3
Higher biologically effective dose of radiotherapy is associated with improved outcomes for locally advanced non-small cell lung carcinoma treated with chemoradiation: an analysis of the Radiation Therapy Oncology Group.更高的生物有效剂量放疗与同期放化疗治疗局部晚期非小细胞肺癌的改善结局相关:放射治疗肿瘤学组的分析。
Int J Radiat Oncol Biol Phys. 2012 Jan 1;82(1):425-34. doi: 10.1016/j.ijrobp.2010.09.004. Epub 2010 Oct 25.
4
21 years of biologically effective dose.21 年的生物有效剂量。
Br J Radiol. 2010 Jul;83(991):554-68. doi: 10.1259/bjr/31372149.
5
Stereotactic body radiation therapy for inoperable early stage lung cancer.立体定向体部放疗治疗不可手术的早期肺癌。
JAMA. 2010 Mar 17;303(11):1070-6. doi: 10.1001/jama.2010.261.
6
Stereotactic body radiation therapy: a comprehensive review.立体定向体部放射治疗:综述
Am J Clin Oncol. 2007 Dec;30(6):637-44. doi: 10.1097/COC.0b013e3180ca7cb1.
7
New technologies in the radiotherapy clinic.放射治疗临床中的新技术。
Front Radiat Ther Oncol. 2007;40:1-17. doi: 10.1159/000106025.
8
Stereotactic radiosurgery and stereotactic body radiation therapy: an overview of technical considerations and clinical applications.立体定向放射外科和立体定向体部放射治疗:技术考量与临床应用概述
Hematol Oncol Clin North Am. 2006 Feb;20(1):87-95. doi: 10.1016/j.hoc.2006.01.009.
9
Tumor response to radiotherapy regulated by endothelial cell apoptosis.肿瘤对放疗的反应受内皮细胞凋亡调控。
Science. 2003 May 16;300(5622):1155-9. doi: 10.1126/science.1082504.
10
Ionizing radiation-induced apoptosis via separate Pms2- and p53-dependent pathways.电离辐射通过独立的Pms2和p53依赖途径诱导细胞凋亡。
Cancer Res. 2000 Sep 1;60(17):4889-93.