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阿片类药物戒毒中苏立文和可乐定治疗效果的比较。

A comparison of suboxone and clonidine treatment outcomes in opiate detoxification.

机构信息

Mary Dee Lane Winston-Salem, NC, USA.

出版信息

Arch Psychiatr Nurs. 2012 Aug;26(4):316-23. doi: 10.1016/j.apnu.2011.10.006. Epub 2012 Jan 12.

DOI:10.1016/j.apnu.2011.10.006
PMID:22835751
Abstract

PURPOSE

This retrospective quality improvement study was to evaluate if Suboxone therapy reduced the risk of terminating treatment against medical advice compared with the use clonidine in men aged 18--55 years.

METHODS

Data were collected through chart review for all opioid-addicted male clients admitted voluntarily to a community-based treatment center between July 1, 2009, and December 30, 2009.

FINDINGS

The chi-square test of independence between treatment completion and treatment noncompletion was found to be significant at the 5% critical level (P = .027) for Suboxone therapy.

CONCLUSIONS

Suboxone treatment decreased premature termination of opioid detoxification completion when compared with clonidine.

摘要

目的

本回顾性质量改进研究旨在评估与使用可乐定相比,丁丙诺啡治疗是否降低了 18-55 岁男性提前终止医嘱治疗的风险。

方法

通过对 2009 年 7 月 1 日至 2009 年 12 月 30 日期间自愿入住社区为基础的治疗中心的所有阿片类药物成瘾的男性患者的图表回顾收集数据。

发现

在 5%的临界水平(P=.027),完成治疗和未完成治疗之间的卡方检验独立显著。

结论

与可乐定相比,丁丙诺啡治疗降低了阿片类药物脱毒完成时过早终止的风险。

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