Barrow P A, Brooker B E, Fuller R, Newport M J, Sojka W J, Wray C, Woode G N
Res Vet Sci. 1979 Jul;27(1):52-8.
When pigs are weaned at two days of age large numbers of Excherichia coli appear in the anterior gut and the incidence of diarrhoea rises. The two phenomena do not appear to be directly related because the strains of E coli isolated are not serotypes previously found to be associated with neonatal pig scouring. Representative strains of the non-enteropathogenic serotypes did not produce enterotoxin and did not adhere to small intestine brush borders. Moreover when antibiotics were fed to eliminate E coli from the gut, the pigs still scoured. Rotavirus was detected in the gut contents and gut epithelium of scouring pigs and a bacteria-free filtrate of gut contents produced diarrhoea when administered to germ-free pigs. It is suggested that rotavirus may be one of the causes of the scouring seen shortly after weaning pigs at two days of age.
当仔猪在2日龄断奶时，大量大肠杆菌出现在前肠，腹泻发生率上升。这两种现象似乎没有直接关联，因为分离出的大肠杆菌菌株并非先前发现与新生仔猪腹泻相关的血清型。非致病性血清型的代表性菌株不产生肠毒素，也不粘附于小肠刷状缘。此外，当给仔猪喂食抗生素以清除肠道中的大肠杆菌时，仔猪仍然会腹泻。在腹泻仔猪的肠内容物和肠上皮中检测到了轮状病毒，并且当将肠内容物的无细菌滤液施用于无菌仔猪时会引起腹泻。有人提出，轮状病毒可能是仔猪在2日龄断奶后不久出现腹泻的原因之一。
