Dimitrov M, Tablov V, Stratev S
Khirurgiia (Sofiia). 1990;43(3):22-6.
The aim of the study is analgesia of patients in urologic practice with unusual (subanesthetic) ketamine doses from 0.5 to 1 mg/kg body mass. It was applied in 50 men 50 to 70 years of age for the period 1986-1988--in 40 for transurethral resection (TUR) and in 10 for urethrotomy. The average duration of the operative interventions was 25 minutes. After standard premedication--droperiodol, phentanyl, atropine, 30 to 40 minutes before the operation ketamine 0.5--1 mg/kg and diazepam 0.2 mg/kg were administered intravenously and in case of need--maintenance dose from 0.25 to 0.50 mg/kg. Pulse rate, breathing rate and arterial pressure were followed up. Analgesia was evaluated by anesthesiologist, operator and patient. The disadvantages, which have been avoided and the advantages over other types of anesthesia, as well as the final positive assessment, allow recommendation of this form of anesthesia in urologic practice.
本研究的目的是在泌尿外科实践中，使用0.5至1毫克/千克体重的非常规（亚麻醉）氯胺酮剂量对患者进行镇痛。在1986年至1988年期间，对50名年龄在50至70岁的男性进行了应用——40名用于经尿道前列腺切除术（TUR），10名用于尿道切开术。手术干预的平均持续时间为25分钟。在标准术前用药——氟哌利多、芬太尼、阿托品之后，在手术前30至40分钟静脉注射0.5至1毫克/千克氯胺酮和0.2毫克/千克地西泮，如有需要——维持剂量为0.25至0.50毫克/千克。对脉搏率、呼吸率和动脉压进行了跟踪。镇痛效果由麻醉师、手术医生和患者进行评估。已避免的缺点、相对于其他类型麻醉的优点以及最终的积极评估，使得这种麻醉形式在泌尿外科实践中值得推荐。
