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[人类丘脑网状核中对不同信号强度言语刺激的动态神经元相互作用]

[The dynamic neuronal interactions in the reticular nucleus of the human thalamus to verbal stimuli of differing signal strengths].

作者信息

Raeva S N, Lukashev A O, Kadin A L, Vasin N Ia, Shabalov V A, Grokhovskiĭ N P

出版信息

Neirofiziologiia. 1990;22(4):451-9.

PMID:2284022
Abstract

Dynamics of neuronal interaction in 90 ensembles of the RT including units of two types (A, B) recorded by microelectrodes was analyzed during verbal and sensory stimulation and voluntary motor acts in dyskinetic patients in the course of 38 stereotaxic operations. It was shown that high transient interneuronal cooperation in A and B units were selectively related to triggering stages of a purposive act: verbal commands presentation and movement initiation and realization. Specific character of dynamics of interneuronal cooperation determined both by the type of constituent elements and functionally different stages of voluntary acts was found. It is supposed that transient interneuronal cooperation of A and B units reflects dynamic conjugation of two functionally different cellular subsystems in the Rt which are probably connected with verbal-related processing and triggering as well as with movement-related voluntary acts.

摘要

在38次立体定向手术过程中,对运动障碍患者在言语和感觉刺激以及自主运动行为期间,通过微电极记录的90个包含两种类型(A、B)神经元的红核神经团簇中的神经元相互作用动力学进行了分析。结果表明,A和B单位中高度短暂的神经元间合作与有目的行为的触发阶段选择性相关:言语指令呈现、运动起始和实现。发现神经元间合作动力学的特定特征既由组成元素的类型决定,也由自主行为功能不同阶段决定。据推测,A和B单位的短暂神经元间合作反映了红核中两个功能不同的细胞子系统的动态结合,这两个子系统可能与言语相关处理和触发以及与运动相关的自主行为有关。

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