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[磁共振成像在膝关节关节内病变诊断中的应用]

[Magnetic resonance imaging in the diagnosis of intra-articular lesions of the knee].

作者信息

Cellár R, Sokol D, Lacko M, Štolfa Š, Gharaibeh A, Vaško G

机构信息

Klinika ortopédie a traumatológie pohybového ústrojenstva, LF UPJŠ, UN L. Pasteura, Košice.

出版信息

Acta Chir Orthop Traumatol Cech. 2012;79(3):249-54.

Abstract

PURPOSE OF THE STUDY

Magnetic resonance imaging (MRI) has the highest sensitivity of all methods for the diagnosis of intra-articular knee injuries. In spite of this, its benefit for the decision-making algorithm is questionable. The aim of this study was to evaluate the real situation in our regional conditions.

MATERIAL AND METHODS

The medical records of the patients who underwent knee arthroscopy in 2008 and 2009, and had pre-operative MRI examination, were retrospectively reviewed. The group included 92 patients (46 women and 46 men; average age, 41.7 years) of whom 49 had knee injury in their medical history.

RESULTS

In medial meniscus (MM) injuries, the MRI examination had a sensitivity of 0.92 and a specificity of 0.44, and the congruence of MRI and arthroscopic findings was 0.73. In lateral meniscus (LM) tears, the values were 0.70 for sensitivity, 0.81 for specificity and 0.87 for congruence. In injury to the anterior cruciate ligament (ACL), MRI sensitivity was 0.66, specificity was 0.85 and congruence was 0.79. In evaluation of articular chondral lesions, the values were 0.45 for sensitivity, 0.87 for specificity and 0.60 for congruence.

DISCUSSION

In our examination of knee structures for MM, LM, ACL and cartilage injuries, the diagnostic value of MRI was lowest for cartilage damage, with sensitivity being only 0.45. This was in agreement with the findings of other authors. Although this fact is known, our arthroscopic findings in patients with no MRI evidence of injury were very high: 22 knees with grade III or grade IV chondral lesions. Therefore, MRI examination is not considered to be sensitive enough to replace arthroscopy in the diagnosis of cartilage injuries. MRI examination is most frequently indicated in suspected meniscal damage. Its sensitivity reported in the literature varies; generally, it is about 0.90 in MM injuries, and about 0.75 in LM lesions, and this is in agreement with our results. However, in view of our previous experience, the high sensitivity of MRI in the diagnosis of MM lesions was an unexpected finding. A detailed statistical analysis showed that its high value was at the expense of a relatively high negative positivity (0.56) and a low predictive value of the positive test (0.65). In LM injuries these values were even worse: in addition to low sensitivity (0.70), the predictive value of the positive test was only 0.50. In the diagnosis of ACL injuries, MRI examination is reported to have a high sensitivity ranging from 0.85 to 0.90. This study showed poorer results; sensitivity was 0.66 and the predictive value of the positive test was 0.62. For injuries in which the orthopaedist is sure about the diagnosis and indicates arthroscopy, it is doubtful to indicate also MRI examination. This should be reserved for clinical presentations that are not clear, for post-operative conditions, serious knee injuries or combined injuries. However, patients with chronic problems and unclear clinical presentations should benefit from MRI examination which can make the diagnosis more accurate and thus reduce the number of arthroscopic procedures done entirely for diagnostic purposes.

CONCLUSIONS

There is no consensus regarding the role of MRI in the diagnosis of intra-articular lesions of the knee. To a certain extent, its use is related to local conditions. It can be concluded that MRI examination is not currently as important for the diagnosis of knee injuries as expected by both medical and lay communities.

摘要

研究目的

在诊断膝关节内损伤的所有方法中,磁共振成像(MRI)具有最高的灵敏度。尽管如此,其在决策算法中的益处仍值得怀疑。本研究的目的是评估我们地区的实际情况。

材料与方法

回顾性分析2008年和2009年接受膝关节镜检查且术前进行了MRI检查的患者的病历。该组包括92例患者(46名女性和46名男性;平均年龄41.7岁),其中49例患者有膝关节损伤病史。

结果

在内侧半月板(MM)损伤中,MRI检查的灵敏度为0.92,特异度为0.44,MRI与关节镜检查结果的一致性为0.73。在外侧半月板(LM)撕裂中,灵敏度值为0.70,特异度为0.81,一致性为0.87。在前交叉韧带(ACL)损伤中,MRI灵敏度为0.66,特异度为0.85,一致性为0.79。在评估关节软骨损伤时,灵敏度值为0.45,特异度为0.87,一致性为0.60。

讨论

在我们对膝关节结构进行MM、LM、ACL和软骨损伤的检查中,MRI对软骨损伤的诊断价值最低,灵敏度仅为0.45。这与其他作者的研究结果一致。尽管这一事实是已知的,但我们在没有MRI损伤证据的患者中的关节镜检查结果却非常高:22个膝关节存在III级或IV级软骨损伤。因此,在软骨损伤的诊断中,MRI检查被认为不够敏感,不足以替代关节镜检查。MRI检查最常用于疑似半月板损伤的情况。文献报道的其灵敏度有所不同;一般来说,MM损伤时约为0.90,LM损伤时约为0.75,这与我们的结果一致。然而,鉴于我们之前的经验,MRI在诊断MM损伤时的高灵敏度是一个意外发现。详细的统计分析表明,其高值是以相对较高的假阳性率(0.56)和阳性试验的低预测值(0.65)为代价的。在LM损伤中,这些值更差:除了灵敏度低(0.70)外,阳性试验的预测值仅为0.50。在ACL损伤的诊断中,据报道MRI检查具有较高的灵敏度,范围为0.85至0.90。本研究结果较差;灵敏度为0.66,阳性试验的预测值为0.62。对于骨科医生确定诊断并建议进行关节镜检查的损伤,同时建议进行MRI检查是值得怀疑的。这应该保留给临床表现不明确、术后情况、严重膝关节损伤或复合损伤的情况。然而,患有慢性问题且临床表现不明确的患者应该从MRI检查中受益,这可以使诊断更准确,从而减少完全出于诊断目的而进行的关节镜检查的数量。

结论

关于MRI在膝关节内损伤诊断中的作用尚无共识。在一定程度上,其使用与当地情况有关。可以得出结论,目前MRI检查对膝关节损伤诊断的重要性不如医学界和普通大众预期的那样。

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