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单中心在 Norwood 手术背景下的弓部重建经验。

Single-center experience of arch reconstruction in the setting of Norwood operation.

机构信息

Department of Cardiac Surgery, Birmingham Children's Hospital, Birmingham, United Kingdom.

出版信息

Ann Thorac Surg. 2012 Nov;94(5):1534-9. doi: 10.1016/j.athoracsur.2012.05.097. Epub 2012 Jul 26.

Abstract

BACKGROUND

Arch reconstruction is a key part of the Norwood operation for hypoplastic left heart syndrome and is related to late morbidity. Since 2003, our surgical technique has been standardized to a right ventricle to pulmonary artery conduit, arch reconstruction with homograft patch, and Damus-Kaye-Stansel anastomosis onto homograft patch, with partial or complete resection of any coarctation ridge. We studied the impact of the surgical approach on arch reinterventions and outcome.

METHODS

A retrospective review of echocardiogram, catheterizations, and hospital records of patients who underwent stage1 reconstruction from January 2003 to December 2010 was performed.

RESULTS

A total of 289 patients underwent stage 1 reconstruction during this period. Age and body weight at operation were 9.3 ± 25 days and 3.1 ± 0.6 kg. Early survival was 86%. Seventy-three patients (25%) underwent intervention for recoarctation: balloon angioplasty (n = 68) or surgical intervention (n = 11). Eighteen patients underwent multiple interventions for recoarctation. Size of ascending aorta and incomplete resection of ductal tissue were risk factors for reintervention (p = 0.01 and p = 0.02). Patients with an ascending aorta diameter less than 2 mm had significantly higher reintervention rates (p = 0.01).

CONCLUSIONS

Our standard technique for the Norwood operation has good results but further intervention for recoarctation is common. Size of ascending aorta and incomplete resection of coarctation tissue were risk factors for recoarctation. Complete resection of coarctation tissue may reduce the incidence of recoarctation. A small ascending aorta may predict late arch problems.

摘要

背景

左心发育不全综合征的诺伍德手术的关键部分是弓重建,这与迟发性发病率有关。自 2003 年以来,我们的手术技术已经标准化,采用右心室肺动脉导管、同种异体补片弓重建和同种异体补片上的达姆斯-凯伊-斯坦塞尔吻合术,同时部分或完全切除任何缩窄嵴。我们研究了手术方法对弓再干预和结果的影响。

方法

对 2003 年 1 月至 2010 年 12 月期间接受一期重建的患者的超声心动图、心导管检查和住院记录进行了回顾性分析。

结果

在此期间,共有 289 例患者接受了一期重建。手术时的年龄和体重分别为 9.3±25 天和 3.1±0.6kg。早期存活率为 86%。73 例(25%)患者因再狭窄而行介入治疗:球囊血管成形术(n=68)或手术干预(n=11)。18 例患者因再狭窄而行多次介入治疗。升主动脉大小和未完全切除导管组织是再干预的危险因素(p=0.01 和 p=0.02)。升主动脉直径小于 2mm 的患者再干预率明显较高(p=0.01)。

结论

我们的诺伍德手术标准技术有良好的效果,但再狭窄的进一步干预是常见的。升主动脉大小和未完全切除缩窄组织是再狭窄的危险因素。完全切除缩窄组织可能会降低再狭窄的发生率。小的升主动脉可能预示着晚期弓部问题。

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