[Melanoblastoma of the meninges. Immunohistochemical and ultrastructural study of a case].

Primary diffuse melanoblastomatosis of the leptomeninges is an uncommon disease and are not associated with any specific clinical or radiologic features. Diagnosis is usually post-mortem and first regard the interpretation of malignant melanoblastomatosis as a primary neoplasm; the situation is complicated by the fact that a primary melanoma, in this site, may metastasize to extraneural organs and a detailed dissection of the entire body, including the orbital contents, aims to reveal no primary tumor outside the nervous system. Differential diagnosis is V.S. others pigmented tumors of the C.N.S. Electronmicroscopic and immunohistochemical analysis were performed and confirmed the diagnosis.