Operative Unit for Recovery and Functional Rehabilitation, Fondazione Salvatore Maugeri IRCCS, Via G. Mazzini 129, 25066 Lumezzane (BS), Italy.
Aging Clin Exp Res. 2012 Apr;24(2):197-9. doi: 10.1007/BF03325165.
To describe the unusual course of a patient with cerebellar ataxia who underwent rehabilitation.
At admission, the patient underwent motor rehabilitation and assessment by Tinetti Assessment, Klockgether Score, National Institute of Health Stroke Scale, Trunk Control Test, Fugl-Meyer Scale, Barthel Index, and Mini Mental State Examination.
The patient showed very rapid and severe decline of motor and functional tests during the first month of hospitalization and complete dependence in <2 months, despite rehabilitation. He died 10 months after onset, with a neuro-pathological diagnosis of sporadic Creutzfeldt-Jakob disease (CJD).
Our case report suggests that sporadic CJD must be hypothesized when ataxia worsens rapidly and severely despite rehabilitation.
描述一名小脑共济失调患者在接受康复治疗过程中的不寻常病程。
入院时，患者接受了运动康复治疗，并进行了 Tinetti 评估、Klockgether 评分、国立卫生研究院卒中量表、躯干控制测试、Fugl-Meyer 量表、Barthel 指数和简易精神状态检查。
尽管进行了康复治疗，但患者在住院的第一个月内运动和功能测试迅速而严重地下降，不到 2 个月就完全依赖他人。他在发病后 10 个月死亡，神经病理学诊断为散发性克雅氏病（CJD）。
我们的病例报告提示，当尽管进行了康复治疗，共济失调仍迅速且严重恶化时，必须假设散发性 CJD。
