Department of Orthopedic Surgery, Chonbuk National University Hospital, Chonbuk National University Medical School, Research Institute of Clinical Medicine, 634-18 Keuam-dong, Jeonju, Chonbuk, South Korea.
Eur Spine J. 2012 Dec;21(12):2492-7. doi: 10.1007/s00586-012-2447-0. Epub 2012 Jul 28.
Three- or four-level anterior cervical discectomy and fusion with autograft and plate fixation have demonstrated relatively good fusion rates and outcomes, but donor site morbidity and the limitations of autograft harvest remain problematic. The purpose of this study is to assess the radiographic and clinical outcomes of three- or four-level anterior cervical discectomy and fusion with a PEEK cage and plate construct.
This retrospective review included 43 consecutive patients who underwent three- or four-level anterior cervical discectomy and fusion with a PEEK cage and plate construct (three level: 39 cases, four level: 4 cases). The fusion rate, time to fusion, Cobb angle and disc height were assessed radiographically. Clinical outcomes were evaluated with the VAS, NDI, and SF36 scores. Complications were also recorded.
Solid fusion was achieved in all the patients, and mean time to fusion was 13.7 ± 5.1 weeks. The postoperative Cobb angle, lordotic angle, and disc height (5.6°, 10.5° and 3.15 mm, respectively) increased significantly compared to preoperative values (p = 0.038, p = 0.032, and p = 0.0004, respectively), and these improvements were maintained through final follow-up. The postoperative NDI (17.2), VAS (2.8), and SF36 (13.1) scores increased significantly compared to the preoperative scores (p = 0.026, p = 0.0007 and p = 0.041, respectively). Complications included three cases of respiratory difficulty, four cases of dysphagia and one case of hoarseness. There were no cases of donor site morbidity.
Three- or four-level anterior cervical discectomy and fusion with a PEEK cage, and plate construct provide good clinical and radiographic outcomes including high fusion rates, low complication rates, low donor site morbidity, and good maintenance of the lordotic angle and disc height in the treatment of multilevel cervical spondylosis.
三或四节颈椎前路椎间盘切除融合术联合自体植骨和钢板固定已显示出相对较好的融合率和结果,但供区并发症和自体骨采集的局限性仍然是个问题。本研究旨在评估三或四节颈椎前路椎间盘切除融合术联合聚醚醚酮(PEEK) cage 和钢板固定的影像学和临床结果。
这是一项回顾性研究,共纳入 43 例连续接受三或四节颈椎前路椎间盘切除融合术联合 PEEK cage 和钢板固定的患者(三节段:39 例,四节段:4 例)。通过影像学评估融合率、融合时间、Cobb 角和椎间盘高度。通过视觉模拟评分(VAS)、颈椎功能障碍指数(NDI)和健康调查简表 36 项(SF-36)评分评估临床结果。还记录了并发症。
所有患者均获得了骨性融合,融合时间的平均时间为 13.7 ± 5.1 周。术后 Cobb 角、前凸角和椎间盘高度(分别为 5.6°、10.5°和 3.15mm)与术前相比显著增加(p = 0.038,p = 0.032 和 p = 0.0004),这些改善在最终随访时得以维持。术后 NDI(17.2)、VAS(2.8)和 SF-36(13.1)评分与术前相比显著增加(p = 0.026,p = 0.0007 和 p = 0.041)。并发症包括 3 例呼吸困难、4 例吞咽困难和 1 例声音嘶哑。无供区并发症。
三或四节颈椎前路椎间盘切除融合术联合 PEEK cage 和钢板固定在治疗多节段颈椎病方面提供了良好的临床和影像学结果,包括较高的融合率、较低的并发症发生率、较低的供区并发症发生率以及较好地维持前凸角和椎间盘高度。