成人隐匿性自身免疫性糖尿病的诊断标准（LADA）：综述与反思。
Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection.
机构信息
Diabetes Center, 2nd Xiangya Hospital, and Institute of Metabolism and Endocrinology, Key Laboratory of Diabetes Immunology, Ministry of Education, Central South University, Changsha 410011, China.
出版信息
Front Med. 2012 Sep;6(3):243-7. doi: 10.1007/s11684-012-0201-y. Epub 2012 Jul 28.
Diabetes has become a major public health problem in China nowadays. There are almost 97 million diabetic patients nationwide. Latent autoimmune diabetes in adults (LADA) is a subtype of autoimmune diabetes. Although it has been reported for about 20 years, the diagnostic criteria of this disease remain controversial. The discussion mainly focused on serum autoantibodies, period of insulin need and age of diagnosis. Besides, β cell function, metabolic parameters, genetic factors and cell immunity may also contribute to the formulation of the criteria. Here, we aim to review and discuss the diagnostic criteria of latent autoimmune diabetes in adults.
糖尿病现已成为中国主要的公共卫生问题之一。全国几乎有 9700 万糖尿病患者。成人隐匿性自身免疫性糖尿病（LADA）是一种自身免疫性糖尿病的亚型。虽然这种疾病已经报道了大约 20 年，但该疾病的诊断标准仍存在争议。讨论主要集中在血清自身抗体、胰岛素需求时间和诊断年龄上。此外，β细胞功能、代谢参数、遗传因素和细胞免疫也可能有助于制定标准。在这里，我们旨在回顾和讨论成人隐匿性自身免疫性糖尿病的诊断标准。
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