Dange Nitin, Redhu Rakesh, Kawale Juhi, Mahore Amit
Kem Hospital, Department of Neurosurgery, Mumbai, India.
Turk Neurosurg. 2012;22(4):499-501. doi: 10.5137/1019-5149.JTN.3901-10.0.
We report a 16-year-old girl who had stunted growth and primary amenorrhea presenting with headache and vomiting. MRI of brain showed posterior fossa dermoid cyst with hydrocephalus and empty sella. Growth hormone (GH), Leutinizing hormone (LH) and Follicular stimulating hormone (FSH) were grossly reduced on endocrinological work-up. She underwent suboccipital midline craniectomy and complete excision of dermoid cyst .She had no additional deficit after the surgery. She had menarche six months after the surgery and developed adequate secondary sexual characters, however her height remains subnormal at follow-up after 2 years as compared to age matched controls. We briefly review the radiological features, pathogenesis and outcome of this underestimated entity.
我们报告一名16岁女孩，她生长发育迟缓且原发性闭经，伴有头痛和呕吐。脑部MRI显示后颅窝皮样囊肿伴脑积水和空蝶鞍。内分泌检查显示生长激素（GH）、促黄体生成素（LH）和促卵泡生成素（FSH）显著降低。她接受了枕下中线颅骨切除术并完整切除了皮样囊肿。术后她没有出现其他功能缺损。术后6个月她月经初潮，并发育出了充分的第二性征，然而与年龄匹配的对照组相比，随访2年后她的身高仍低于正常水平。我们简要回顾了这个被低估的疾病的放射学特征、发病机制和预后。
