Yu Jinlu, Qu Li Mei, Li Ye, Huang Haiyan
First Hospital of Jilin University, Department of Neurosurgery, Changchun, China.
Turk Neurosurg. 2012;22(4):510-4. doi: 10.5137/1019-5149.JTN.3961-10.1.
The coexistence of spinal teratoma of the conus medullaris and arteriovenous malformation (AVM) is exceptional, which has not been reported previously in the literature. The precise mechanism of the coexistence of these conditions is not known, however, the dysembryonic origin of spinal cord teratoma and AVM seems to play a part in this process. A 34-year-old male patient was admitted with lower back pain, bilateral lower extremity numbness and weakness, and sexual disturbance. Magnetic resonance imaging (MRI) showed an AVM extended cranially from the top of a heterogeneous expansile lesion of the conus medullaris. Surgical exploration and histopathological examination revealed a mature teratoma associated with the AVM. A literature review supported the dysembryonic origin of spinal cord teratomas and AVMs. This unique case may provide insight into the etiopathogenesis of the coexistence of spinal teratoma of the conus medullaris and AVM.
圆锥脊髓畸胎瘤与动静脉畸形(AVM)并存的情况极为罕见,此前文献中尚无相关报道。虽然这些病症并存的确切机制尚不清楚,但脊髓畸胎瘤和AVM的胚胎发育异常起源似乎在这一过程中起到了一定作用。一名34岁男性患者因下背部疼痛、双侧下肢麻木无力及性功能障碍入院。磁共振成像(MRI)显示一个AVM从圆锥脊髓的一个异质性膨胀性病变顶部向头侧延伸。手术探查和组织病理学检查发现一个与AVM相关的成熟畸胎瘤。文献综述支持脊髓畸胎瘤和AVM的胚胎发育异常起源。这一独特病例可能为圆锥脊髓畸胎瘤与AVM并存的病因学提供见解。