Veterinary Immunology Research Institute of Northwest A & F University, College of Veterinary Medicine, Northwest A & F University, Yangling, Shaanxi, China.
J Virol. 2012 Aug;86(16):8906. doi: 10.1128/JVI.01281-12.
Following the 2006 outbreaks of the highly pathogenic porcine reproductive and respiratory syndrome, the causative agent was identified as the highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV). To investigate whether the HP-PRRSV variant continues circulating and accelerating evolution, we sequenced and analyzed the complete genome of the identified HP-PRRSV field strain SD16. The sequence data indicate that the HP-PRRSV variant continues to prevail and accelerate evolution, especially in the nonstructural protein.
继 2006 年高致病性猪繁殖与呼吸综合征爆发后，该病原体被鉴定为高致病性猪繁殖与呼吸综合征病毒（HP-PRRSV）。为了研究 HP-PRRSV 变异株是否持续流行并加速进化，我们对鉴定出的 HP-PRRSV 田间毒株 SD16 进行了全基因组测序和分析。序列数据表明，HP-PRRSV 变异株仍在持续流行并加速进化，尤其是在非结构蛋白中。
