Department of Urology, North Hospital, CHU of Saint Etienne, 42055 Saint-Etienne cedex 2, France.
Anticancer Res. 2012 Aug;32(8):3463-6.
Our aim was to evaluate the performance of combination of fine-needle aspiration (FNA) and core biopsy (CB) as a method for the diagnosis of small solid renal tumors.
Ninety patients with a radiologically detected small solid renal tumor (≤ 4 cm) underwent a biopsy. Patient underwent FNA (FNA group, n=32) or CB (CB group, n=30) or combination of both FNA and CB (combination group, n=28). The diagnostic rate and accuracy of both techniques were assessed.
The diagnostic rate of the combination group (92.9%) was superior to that of the FNA group (62.5%) and CB group (76.7%) (p=0.006, and p=0.147, respectively). In the combination group, 11 CBs were diagnostic with 13 nondiagnostic FNAs, while 4 FNAs were diagnostic with 6 nondiagnostic CBs. For tumors ≤ 2 cm, the combination of FNA and CB significantly increased the diagnostic rate, compared with FNA alone (p=0.033) and CB alone (p=0.044). The accuracy for FNA, CB and the combination of FNA and CB was 88%, 100% and 100%, respectively.
The combination of FNA and CB increased the diagnostic rate of renal biopsy for the small solid renal tumors.
我们旨在评估细针抽吸（FNA）和核心活检（CB）联合作为诊断小实体肾肿瘤方法的性能。
90 名经影像学检测到的小实体肾肿瘤（≤4cm）患者接受了活检。患者接受了 FNA（FNA 组，n=32）或 CB（CB 组，n=30）或 FNA 和 CB 联合（联合组，n=28）。评估了两种技术的诊断率和准确性。
联合组（92.9%）的诊断率优于 FNA 组（62.5%）和 CB 组（76.7%）（p=0.006 和 p=0.147）。在联合组中，11 例 CB 为诊断性，13 例 FNA 为非诊断性，而 4 例 FNA 为诊断性，6 例 CB 为非诊断性。对于≤2cm 的肿瘤，与单独 FNA（p=0.033）和单独 CB（p=0.044）相比，FNA 和 CB 的联合显著提高了诊断率。FNA、CB 和 FNA 和 CB 联合的准确性分别为 88%、100%和 100%。
FNA 和 CB 的联合增加了小实体肾肿瘤肾活检的诊断率。
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