奥沙利铂诱导弥散性血管内凝血：病例报告及文献复习。
Oxaliplatin induced disseminated intravascular coagulation: A case report and review of literature.
机构信息
Shweta Kurian, Jessica Macintyre, Muzammil Mushtaq, Caio Max Rocha-Lima, Yeon Ahn, Division of Hematology Oncology, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL 33136, United States.
出版信息
World J Gastrointest Oncol. 2012 Jul 15;4(7):181-3. doi: 10.4251/wjgo.v4.i7.181.
Abstract
Oxaliplatin in combination with a fluoropyrimide is a treatment option for colorectal cancer patients in the adjuvant and metastatic settings. Very few hematological emergencies have been reported associated with Oxaliplatin. These include autoimmune hemolytic anemia, thrombocytopenia and pancytopenia. We present a case report of a patient who developed hematuria and disseminated intravascular coagulation while receiving the second cycle of FOLFOX and bevacizumab for metastatic colon cancer.
摘要
奥沙利铂联合氟嘧啶是结直肠癌患者辅助治疗和转移性疾病治疗的一种选择。与奥沙利铂相关的血液学急症非常少见，包括自身免疫性溶血性贫血、血小板减少症和全血细胞减少症。我们报告了一例转移性结肠癌患者在接受 FOLFOX 和贝伐单抗第二周期治疗时发生血尿和弥漫性血管内凝血的病例。
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Fatal thrombocytopenia after oxaliplatin-based chemotherapy.基于奥沙利铂的化疗后出现致命性血小板减少症。
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Life-threatening oxaliplatin-induced acute thrombocytopenia, hemolysis and bleeding: a case report.危及生命的奥沙利铂诱导的急性血小板减少、溶血和出血：一例报告
Acta Oncol. 2008;47(8):1602-4. doi: 10.1080/02841860801978913.
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Oxaliplatin-induced immune mediated thrombocytopenia.奥沙利铂诱导的免疫介导性血小板减少症。
Cancer Chemother Pharmacol. 2008 Oct;62(5):925-7. doi: 10.1007/s00280-007-0675-5. Epub 2008 Jan 19.
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Oxaliplatin-induced hemolytic anemia during adjuvant treatment of a patient with colon cancer: a case report.奥沙利铂在一名结肠癌患者辅助治疗期间引起溶血性贫血：一例病例报告
Anticancer Drugs. 2007 Mar;18(3):297-300. doi: 10.1097/CAD.0b013e3280102f4b.
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Oxaliplatin-induced immune thrombocytopenia.
Gastroenterol Clin Biol. 2006 May;30(5):797-8. doi: 10.1016/s0399-8320(06)73320-6.
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Immune-mediated thrombocytopenia resulting from sensitivity to oxaliplatin.由对奥沙利铂敏感引起的免疫介导性血小板减少症。
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