Department of Public Health, University of California, Berkeley, Berkeley, California 94720, USA.
Psychophysiology. 2012 Sep;49(9):1200-14. doi: 10.1111/j.1469-8986.2012.01443.x. Epub 2012 Jul 27.
Research indicates that dorsolateral prefrontal cortex (DLPFC) is important for pursuing goals, and areas of DLPFC are differentially involved in approach and avoidance motivation. Given the complexity of the processes involved in goal pursuit, DLPFC is likely part of a network that includes orbitofrontal cortex (OFC), cingulate, amygdala, and basal ganglia. This hypothesis was tested with regard to one component of goal pursuit, the maintenance of goals in the face of distraction. Examination of connectivity with motivation-related areas of DLPFC supported the network hypothesis. Differential patterns of connectivity suggest a distinct role for DLPFC areas, with one involved in selecting approach goals, one in selecting avoidance goals, and one in selecting goal pursuit strategies. Finally, differences in trait motivation moderated connectivity between DLPFC and OFC, suggesting that this connectivity is important for instantiating motivation.
研究表明，背外侧前额叶皮层（DLPFC）对于追求目标很重要，并且 DLPFC 的不同区域与接近和回避动机有关。鉴于目标追求过程的复杂性，DLPFC 可能是包括眶额皮层（OFC）、扣带、杏仁核和基底神经节在内的网络的一部分。这一假说在面对干扰时维持目标这一目标追求的一个组成部分方面得到了检验。与 DLPFC 与动机相关区域的连通性的检查支持了网络假说。连通性的差异模式表明 DLPFC 区域具有不同的作用，一个区域参与选择接近目标，一个区域参与选择回避目标，一个区域参与选择目标追求策略。最后，特质动机的差异调节了 DLPFC 和 OFC 之间的连通性，这表明这种连通性对于实现动机很重要。
