Department of Chemistry, Division of IBB, Pohang University of Science and Technology, Pohang 790-784, Korea.
Chem Commun (Camb). 2012 Sep 14;48(71):8901-3. doi: 10.1039/c2cc34466a. Epub 2012 Jul 31.
A low-molecular-weight hydrogel derived from riboflavin (vitamin B(2)) that self-assembles to provide supramolecular nanofibers, biocompatible material, can be used to deliver VEGF-siRNA efficiently into human cells by the endocytosis pathway, where the siRNA is functionalized.
一种由核黄素(维生素 B(2))衍生的低分子量水凝胶,通过自组装提供超分子纳米纤维,是一种生物相容性材料,可通过细胞内吞途径将 VEGF-siRNA 有效地递送到人细胞中,其中 siRNA 被功能化。