Department of Otolaryngology, Imperial College Hospitals NHS Trust, London, United Kingdom.
Head Neck. 2013 Sep;35(9):E264-6. doi: 10.1002/hed.23121. Epub 2012 Jul 30.
The long-term use of highly active antiretroviral therapy (HAART) in patients with human immunodeficiency virus (HIV) has led to sequelae including lipodystrophy syndrome (LDS). We present the first published case of surgical management of bilateral parotid lipomatosis in a patient with HIV on long-term HAART.
We undertook review of the case notes from the time of diagnosis with HIV and literature review of this topic.
A 45-year-old man with HIV on HAART presented with a 4-year history of increasing bilateral facial swelling. He was asymptomatic apart from the stigmatizing cosmetic deformity. MRI revealed the parotid glands had been replaced by fat. He elected for surgery and parotid lipomatosis was diagnosed on histopathological examination.
Lipohypertrophy in LDS is rare in the literature and this presentation of bilateral parotid lipomatosis secondary to HAART is only the third reported case, and the first to undergo surgical resection.
人类免疫缺陷病毒（HIV）患者长期使用高效抗逆转录病毒疗法（HAART）会导致脂肪营养不良综合征（LDS）等后遗症。我们报告首例 HIV 患者长期接受 HAART 后行双侧腮腺脂肪增多症手术治疗的病例。
我们对该患者 HIV 确诊时的病历进行了回顾，并对该主题的文献进行了复习。
一名 45 岁男性 HIV 患者，长期接受 HAART，4 年来双侧面部逐渐肿胀。除了令人感到耻辱的美容畸形外，他无症状。MRI 显示腮腺被脂肪替代。他选择手术，组织病理学检查诊断为腮腺脂肪增多症。
文献中 LDS 的脂肪增生罕见，本报告中 HAART 引起的双侧腮腺脂肪增多症是第三例报道，也是首例接受手术切除的病例。
