Osungbade Kayode O, Oladunjoye Adeolu O
Department of Health Policy and Management, Faculty of Public Health, College of Medicine and University College Hospital, University of Ibadan, P.M.B. 5017 General Post Office, Ibadan, Nigeria.
J Pregnancy. 2012;2012:454601. doi: 10.1155/2012/454601. Epub 2012 Jul 10.
We conducted a review of effectiveness of preventive treatments of iron deficiency anaemia in pregnancy in developing countries and highlighted their constraints as well as interventions required to strengthen the health services. Methods. Literature from Pubmed (MEDLINE), AJOL, Google Scholar, and Cochrane database was reviewed.
Evidence-based preventive treatment options for iron deficiency anaemia in pregnancy include prophylaxis iron supplements and food fortification with iron. Evidence abounds on their effectiveness in reducing the prevalence of iron deficiency anaemia in pregnancy. However, these prospects are threatened by side effects of iron supplements, low utilization of maternal health service in developing countries, partial implementation of preventive treatments, and weak infrastructure and political commitment to implement mass fortification of local staple foods by national governments.
Sustainability of effectiveness of preventive treatments of iron deficiency anaemia in pregnancy could be achieved if the identified threats are adequately addressed.
我们对发展中国家孕期缺铁性贫血预防性治疗的有效性进行了综述，并强调了其限制因素以及加强卫生服务所需的干预措施。方法：对来自PubMed（MEDLINE）、AJOL、谷歌学术和Cochrane数据库的文献进行了综述。
孕期缺铁性贫血的循证预防性治疗选择包括预防性铁补充剂和铁强化食品。关于它们在降低孕期缺铁性贫血患病率方面的有效性，有大量证据。然而，这些前景受到铁补充剂的副作用、发展中国家孕产妇保健服务利用率低、预防性治疗的部分实施以及国家政府实施当地主食大规模强化的基础设施薄弱和政治承诺不足的威胁。
如果充分应对已确定的威胁，孕期缺铁性贫血预防性治疗的有效性可持续性是可以实现的。
