Krispin T I, Kol'tsov V D, Balandin I G
Vopr Virusol. 1979 Sep-Oct(5):510-4.
After contact with mouse culture interferon in the cold, the resistance to viruses in L cells develops only after the cells are placed into a thermostate at 37 degrees C. The use of colcemide destroying microtubules prevents the development of this resistance at an early (actinomycin-sensitive) stage of interferon-cell interaction. In the actinomycin-resistant stage, however, colcemide practically exerts no influence on the interferon-induced resistance to viruses.
在低温下与小鼠培养干扰素接触后，L细胞对病毒的抵抗力只有在细胞置于37℃的恒温箱中后才会产生。使用破坏微管的秋水仙酰胺可在干扰素与细胞相互作用的早期（对放线菌素敏感）阶段阻止这种抵抗力的产生。然而，在对放线菌素耐药的阶段，秋水仙酰胺实际上对干扰素诱导的病毒抵抗力没有影响。
