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[一例以低位颅神经病变为表现的变应性肉芽肿性血管炎]

[A case of Churg-Strauss syndrome presenting with lower cranial neuropathy].

作者信息

Shimada Takuya, Sasaki Ryogen, Ii Yuichiro, Taniguchi Akira, Ueda Yukito, Tomimoto Hidekazu

机构信息

Department of Neurology, Mie University Hospital.

出版信息

Rinsho Shinkeigaku. 2012;52(7):507-10. doi: 10.5692/clinicalneurol.52.507.

Abstract

We reported a 60 year-old man with Churg-Strauss syndrome (CSS). Three months later, he presented with dysarthria, dysphagia and severe headache. We detected glossopharyngeal and vagal nerve palsy, and made a diagnosis of cranial nerve involvement comorbid with CSS. Intravenous administration of methypredonisolone was effective for alleviating clinical signs and symptoms. Two months later, he complained of headache and facial numbness, but symptoms improved with an escalating dose of prednisolon. As compared to previously reported cases, our case was characteristic because of involvement of lower cranial nerve with CSS, which has been reported previously in only one case.

摘要

我们报告了一名60岁患有变应性肉芽肿性血管炎(CSS)的男性患者。三个月后,他出现构音障碍、吞咽困难和严重头痛。我们检测到舌咽神经和迷走神经麻痹,并诊断为与CSS合并的颅神经受累。静脉注射甲泼尼龙对缓解临床体征和症状有效。两个月后,他诉说头痛和面部麻木,但随着泼尼松龙剂量的增加症状有所改善。与先前报道的病例相比,我们的病例具有特征性,因为CSS累及了较低的颅神经,此前仅有一例报道过这种情况。

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