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布比卡因用于关节镜检查后镇痛。一项前瞻性、随机、盲法评估。

Postarthroscopy analgesia with bupivacaine. A prospective, randomized, blinded evaluation.

作者信息

Henderson R C, Campion E R, DeMasi R A, Taft T N

机构信息

Division of Orthopaedics, University of North Carolina, Chapel Hill 27599.

出版信息

Am J Sports Med. 1990 Nov-Dec;18(6):614-7. doi: 10.1177/036354659001800610.

Abstract

The analgesic effect of intraarticular bupivacaine injected at the conclusion of knee arthroscopy done under general anesthesia was investigated in a prospective, randomized, and blinded fashion. Pain scores, the use of analgesic medications, crutch use, weight-bearing, activity level, and difficulty sleeping the night after surgery were all unaffected by the use of bupivacaine. The apparent lack of effect is most likely due to rapid clearance from the knee, leaving only a transient, 1 to 2 hours of potential benefit. In this study, the patients were already quite comfortable during this time period due to the routine use of intraoperative narcotics. The preoperative level of knee discomfort was found to be a major determinant of postoperative discomfort. Other much less important factors were synovial and chondral shaving, sex of the patient, and experience of the surgeon.

摘要

在全身麻醉下进行膝关节镜检查结束时注射关节内布比卡因的镇痛效果,以前瞻性、随机和盲法的方式进行了研究。疼痛评分、镇痛药物的使用、拐杖使用、负重、活动水平以及术后当晚的睡眠困难程度,均未受到布比卡因使用的影响。明显缺乏效果很可能是由于其从膝关节快速清除,仅留下短暂的、1至2小时的潜在益处。在本研究中,由于术中常规使用麻醉剂,在此时间段患者已经相当舒适。发现术前膝关节不适程度是术后不适的主要决定因素。其他不太重要的因素包括滑膜和软骨刨削、患者性别以及外科医生的经验。

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