Dimopoulou C, Ormanns S, Eigenbrod S, Müller-Lisse U, Emmerich B, Reincke M
Medizinische Klinik Campus Innenstadt, Klinikum der LMU, Munich, Germany.
Exp Clin Endocrinol Diabetes. 2012 Sep;120(8):501-4. doi: 10.1055/s-0032-1321810. Epub 2012 Jul 31.
A plasmocytoma involving the pituitary gland is an extremely rare entity, with approximately 22 cases of solitary myeloma or multiple myeloma presenting with sellar mass reported in the literature so far.
Here, we report the case of a 71-year-old female patient affected by an extramedullary IgG-lambda multiple myeloma presenting as a pituitary mass lesion. We summarize the diagnostic approaches that confirmed the diagnosis of multiple myeloma and describe treatment outcome after therapy.
Intrasellar plasmocytoma though rare, should be considered in the differential diagnosis of a pituitary mass lesion, since associated with different therapeutic and prognostic implications. Physicians should be alert for intrasellar plasma cell tumors in case of well preserved anterior pituitary function in combination with cranial nerve neuropathies and sellar destruction.
累及垂体的浆细胞瘤是一种极其罕见的疾病，迄今为止，文献报道中约有22例孤立性骨髓瘤或多发性骨髓瘤表现为鞍区肿块。
在此，我们报告一例71岁女性患者，患有髓外IgG-λ型多发性骨髓瘤，表现为垂体肿块病变。我们总结了确诊多发性骨髓瘤的诊断方法，并描述了治疗后的结果。
鞍内浆细胞瘤虽然罕见，但在垂体肿块病变的鉴别诊断中应予以考虑，因为其具有不同的治疗和预后意义。在前垂体功能良好且伴有颅神经病变和鞍区破坏的情况下，医生应警惕鞍内浆细胞瘤。
