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Urinary angiotensinogen as a biomarker of chronic kidney disease: ready for prime time?

作者信息

Burns Kevin D, Hiremath Swapnil

机构信息

Division of Nephrology, Department of Medicine, Kidney Research Centre, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada.

出版信息

Nephrol Dial Transplant. 2012 Aug;27(8):3010-3. doi: 10.1093/ndt/gfs166.

DOI:10.1093/ndt/gfs166
PMID:22851623
Abstract
摘要

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Urinary angiotensinogen as a biomarker of chronic kidney disease: ready for prime time?尿血管紧张素原作为慢性肾脏病的生物标志物:准备好进入黄金时代了吗?
Nephrol Dial Transplant. 2012 Aug;27(8):3010-3. doi: 10.1093/ndt/gfs166.
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Urinary angiotensinogen as a marker of intrarenal angiotensin II activity associated with deterioration of renal function in patients with chronic kidney disease.尿血管紧张素原作为慢性肾病患者肾内血管紧张素II活性的标志物,与肾功能恶化相关。
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Potential role of urinary angiotensinogen in predicting antiproteinuric effects of angiotensin receptor blocker in non-diabetic chronic kidney disease patients: a preliminary report.尿血管紧张素原在预测血管紧张素受体阻滞剂在非糖尿病慢性肾脏病患者中的降蛋白尿效果中的潜在作用:初步报告。
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Changes in Urinary Angiotensinogen Associated with Deterioration of Kidney Function in Patients with Type 2 Diabetes Mellitus.2型糖尿病患者尿血管紧张素原变化与肾功能恶化的关系
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Treatment of metabolic acidosis in patients with stage 3 chronic kidney disease with fruits and vegetables or oral bicarbonate reduces urine angiotensinogen and preserves glomerular filtration rate.用水果和蔬菜或口服碳酸氢盐治疗 3 期慢性肾脏病患者的代谢性酸中毒可减少尿血管紧张素原并维持肾小球滤过率。
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Elevated urinary angiotensinogen excretion links central and renal hemodynamic alterations.尿血管紧张素原排泄增加与中枢和肾脏血液动力学改变有关。
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Urinary Angiotensinogen Could Be a Prognostic Marker of the Renoprotection of Olmesartan in Metabolic Syndrome Patients.
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J Renin Angiotensin Aldosterone Syst. 2014 Dec;15(4):505-8. doi: 10.1177/1470320314557584. Epub 2014 Nov 7.
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Detailed localization of augmented angiotensinogen mRNA and protein in proximal tubule segments of diabetic kidneys in rats and humans.大鼠和人类糖尿病肾病近端小管节段中血管紧张素原mRNA和蛋白增强表达的详细定位。
Int J Biol Sci. 2014 May 3;10(5):530-42. doi: 10.7150/ijbs.8450. eCollection 2014.
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Identification of leptospiral 3-hydroxyacyl-CoA dehydrogenase released in the urine of infected hamsters.感染仓鼠尿液中释放的钩端螺旋体3-羟酰基辅酶A脱氢酶的鉴定。
BMC Microbiol. 2014 May 21;14:132. doi: 10.1186/1471-2180-14-132.
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Oxidative stress/angiotensinogen/renin-angiotensin system axis in patients with diabetic nephropathy.氧化应激/血管紧张素原/肾素-血管紧张素系统轴在糖尿病肾病患者中的作用。
Int J Mol Sci. 2013 Nov 21;14(11):23045-62. doi: 10.3390/ijms141123045.