用于检测肝硬化肝脏中潜伏的小肝细胞癌的HCCR-1：一项前瞻性队列研究。 - Suppr

HCCR-1 for detecting small hepatocellular carcinoma latent in a cirrhotic liver: a prospective cohort study.

作者信息

Jirun Peng, Zhang Guoxin, Ha Seon-Ah, Kim Hyun Kee, Yoo Jinah, Kim Sanghee, Zhongtian Jin, Zhuqingqing Cui, Lee Youn Soo, Gong Gi Hwan, Yoon Joo Hee, Lee Hae Nam, Kim Sa Jin, Kim Tae Eung, Song Eun Young, Lee Yun Kyung, Park Yong Gyu, Kim Jin Woo

出版信息

Gut. 2012 Oct;61(10):1514-5. doi: 10.1136/gutjnl-2012-301994. Epub 2012 Jul 31.

DOI:10.1136/gutjnl-2012-301994

PMID:22851668

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3437781/

Abstract

摘要

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HCCR-1 for detecting small hepatocellular carcinoma latent in a cirrhotic liver: a prospective cohort study.用于检测肝硬化肝脏中潜伏的小肝细胞癌的HCCR-1：一项前瞻性队列研究。

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Prospective validation of an immunohistochemical panel (glypican 3, heat shock protein 70 and glutamine synthetase) in liver biopsies for diagnosis of very early hepatocellular carcinoma.前瞻性验证免疫组化 panel（磷脂酰糖蛋白 3、热休克蛋白 70 和谷氨酰胺合成酶）在肝活检中的诊断非常早期肝细胞癌的应用。

Gut. 2012 Oct;61(10):1481-7. doi: 10.1136/gutjnl-2011-301862. Epub 2012 Jan 27.

Utility of an immunohistochemical panel consisting of glypican-3, heat-shock protein-70, and glutamine synthetase in the distinction of low-grade hepatocellular carcinoma from hepatocellular adenoma.由磷脂酰肌醇蛋白聚糖-3、热休克蛋白-70和谷氨酰胺合成酶组成的免疫组化检测组合在鉴别低级别肝细胞癌与肝细胞腺瘤中的应用。

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Early HCC: diagnosis and molecular markers.早期肝癌：诊断与分子标志物

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Immunoexpression of Heat Shock Protein 70, Glypican 3, Glutamine Synthetase, and Beta-Catenin in Hepatocellular Carcinoma After Liver Transplantation: Association Between Positive Glypican 3 and Beta-Catenin With the Presence of Larger Nodules.肝移植后肝细胞癌中热休克蛋白70、磷脂酰肌醇蛋白聚糖3、谷氨酰胺合成酶和β-连环蛋白的免疫表达：磷脂酰肌醇蛋白聚糖3和β-连环蛋白阳性与较大结节存在之间的关联

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Concomitant use of heat-shock protein 70, glutamine synthetase and glypican-3 is useful in diagnosis of HBV-related hepatocellular carcinoma with higher specificity and sensitivity.热休克蛋白70、谷氨酰胺合成酶和磷脂酰肌醇蛋白聚糖-3联合使用，对乙肝相关肝细胞癌具有较高的诊断特异性和敏感性。

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Up-regulation of human cervical cancer proto-oncogene contributes to hepatitis B virus-induced malignant transformation of hepatocyte by down-regulating E-cadherin.人类宫颈癌原癌基因的上调通过下调E-钙黏蛋白促进乙型肝炎病毒诱导的肝细胞恶性转化。

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本文引用的文献

Non-invasive diagnosis of hepatocellular carcinoma ≤ 2 cm in cirrhosis. Diagnostic accuracy assessing fat, capsule and signal intensity at dynamic MRI.肝硬化中直径≤2cm 的肝细胞癌的非侵入性诊断。在动态 MRI 中评估脂肪、包膜和信号强度的诊断准确性。

J Hepatol. 2012 Jun;56(6):1317-23. doi: 10.1016/j.jhep.2012.01.004. Epub 2012 Feb 4.

Gut. 2012 Oct;61(10):1481-7. doi: 10.1136/gutjnl-2011-301862. Epub 2012 Jan 27.

The human cervical cancer oncogene protein is a biomarker for human hepatocellular carcinoma.人宫颈癌癌基因蛋白是人类肝细胞癌的一种生物标志物。

Cancer Res. 2004 Aug 1;64(15):5434-41. doi: 10.1158/0008-5472.CAN-03-3665.

Identification and differential expression of novel human cervical cancer oncogene HCCR-2 in human cancers and its involvement in p53 stabilization.新型人类宫颈癌癌基因HCCR-2在人类癌症中的鉴定、差异表达及其在p53稳定中的作用

Oncogene. 2003 Jul 24;22(30):4679-89. doi: 10.1038/sj.onc.1206624.

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HCCR-1 for detecting small hepatocellular carcinoma latent in a cirrhotic liver: a prospective cohort study.

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