Regulation and dysregulation of cardiac ryanodine receptor (RyR2) open probability during diastole in health and disease.
作者信息
Dulhunty Angela F, Beard Nicole A, Hanna Amy D
出版信息
J Gen Physiol. 2012 Aug;140(2):87-92. doi: 10.1085/jgp.201210862.
Abstract
摘要
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Regulation and dysregulation of cardiac ryanodine receptor (RyR2) open probability during diastole in health and disease.健康与疾病状态下舒张期心脏兰尼碱受体（RyR2）开放概率的调节与失调
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本文引用的文献
1
Luminal Ca2+ controls activation of the cardiac ryanodine receptor by ATP.腔钙控制着 ATP 对心脏兰尼碱受体的激活。
J Gen Physiol. 2012 Aug;140(2):93-108. doi: 10.1085/jgp.201110708.
2
Proteins within the intracellular calcium store determine cardiac RyR channel activity and cardiac output.细胞内钙库中的蛋白质决定了心肌 RyR 通道的活性和心输出量。
Clin Exp Pharmacol Physiol. 2012 May;39(5):477-84. doi: 10.1111/j.1440-1681.2012.05704.x.
3
Role of RyR2 phosphorylation at S2814 during heart failure progression.RyR2 在心力衰竭进展过程中 S2814 磷酸化的作用。
Circ Res. 2012 May 25;110(11):1474-83. doi: 10.1161/CIRCRESAHA.112.268094. Epub 2012 Apr 17.
4
Absence of triadin, a protein of the calcium release complex, is responsible for cardiac arrhythmia with sudden death in human.钙释放复合物蛋白三联蛋白的缺失是导致人类心律失常和心源性猝死的原因。
Hum Mol Genet. 2012 Jun 15;21(12):2759-67. doi: 10.1093/hmg/dds104. Epub 2012 Mar 14.
5
Ablation of junctin or triadin is associated with increased cardiac injury following ischaemia/reperfusion.连接蛋白或三联蛋白的消融与缺血/再灌注后心脏损伤增加有关。
Cardiovasc Res. 2012 May 1;94(2):333-41. doi: 10.1093/cvr/cvs119. Epub 2012 Mar 12.
6
Calsequestrin 2 and arrhythmias.钙结合蛋白 2 与心律失常。
Am J Physiol Heart Circ Physiol. 2012 Mar 15;302(6):H1250-60. doi: 10.1152/ajpheart.00779.2011. Epub 2011 Dec 23.
7
Dual role of junctin in the regulation of ryanodine receptors and calcium release in cardiac ventricular myocytes.连接蛋白在调控心肌细胞肌浆网钙释放通道和钙离子释放中的双重作用
J Physiol. 2011 Dec 15;589(Pt 24):6063-80. doi: 10.1113/jphysiol.2011.215988. Epub 2011 Oct 24.
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Dynamic calcium movement inside cardiac sarcoplasmic reticulum during release.心脏肌浆网内钙离子的动态运动在释放过程中。
Circ Res. 2011 Apr 1;108(7):847-56. doi: 10.1161/CIRCRESAHA.111.240234. Epub 2011 Feb 10.
9
Is ryanodine receptor phosphorylation key to the fight or flight response and heart failure?ryanodine 受体磷酸化是否是战斗或逃跑反应和心力衰竭的关键？
J Clin Invest. 2010 Dec;120(12):4197-203. doi: 10.1172/JCI45251. Epub 2010 Nov 22.
10
In the RyR2(R4496C) mouse model of CPVT, β-adrenergic stimulation induces Ca waves by increasing SR Ca content and not by decreasing the threshold for Ca waves.在 CPVT 的 RyR2(R4496C) 小鼠模型中，β-肾上腺素能刺激通过增加 SR Ca 含量而不是通过降低 Ca 波的阈值来诱导 Ca 波。
Circ Res. 2010 Dec 10;107(12):1483-9. doi: 10.1161/CIRCRESAHA.110.227744. Epub 2010 Oct 21.
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