Cho Bomin, Lee Bo-Yeon, Kim Hee-Cheol, Woo Hee-Gweon, Sohn Honglae
Department of Chemistry, Chosun University, 375 Seosuk-Dong, Dong-Gu, Gwangju 501-759, Korea.
J Nanosci Nanotechnol. 2012 May;12(5):4159-62. doi: 10.1166/jnn.2012.5921.
A simply modified biosensor based on protein A-modified distributed Bragg reflectors (DBR) porous silicon (PSi) chip for the detection of human immunoglobin G (IgG) are developed. The fabrication, optical characterization, and surface derivatization of DBR PSi are investigated. The sensor system studied consist of multi-layer of porous silicon modified with protein-A. The sensor is operated by the measurement of the reflection peak in the white light reflection spectrum. Molecular binding is detected as a shift in wavelength of reflection peaks.
开发了一种基于蛋白A修饰的分布式布拉格反射器（DBR）多孔硅（PSi）芯片的简单改进型生物传感器，用于检测人免疫球蛋白G（IgG）。研究了DBR PSi的制备、光学表征和表面衍生化。所研究的传感器系统由用蛋白A修饰的多层多孔硅组成。该传感器通过测量白光反射光谱中的反射峰来运行。分子结合通过反射峰波长的移动来检测。
