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心脏起搏器与乳腺癌放疗：在这种情况下，靶向术中放疗是答案吗？

Pacemaker and radiotherapy in breast cancer: is targeted intraoperative radiotherapy the answer in this setting?

机构信息

The Breast Unit, Academic Department of Surgery, Royal Free and University College Medical School, Pond Street, London, NW3 2QG, UK.

出版信息

Radiat Oncol. 2012 Aug 1;7:128. doi: 10.1186/1748-717X-7-128.

DOI:10.1186/1748-717X-7-128
PMID:22852824
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3484077/
Abstract

We present the case of an 83 year old woman with a cardiac pacemaker located close in distance to a subsequently diagnosed invasive ductal carcinoma of the left breast. Short range intraoperative radiotherapy was given following wide local excision and sentinel node biopsy. The challenges of using ionising radiation with pacemakers is also discussed.

摘要

我们报告了一例 83 岁女性病例，她的心脏起搏器与左乳随后诊断的浸润性导管癌距离较近。在广泛局部切除和前哨淋巴结活检后，给予近距离短程放疗。还讨论了使用起搏器进行电离辐射的挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a60b/3484077/e0877ccbecc3/1748-717X-7-128-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a60b/3484077/22a45b408fe4/1748-717X-7-128-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a60b/3484077/e0877ccbecc3/1748-717X-7-128-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a60b/3484077/22a45b408fe4/1748-717X-7-128-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a60b/3484077/e0877ccbecc3/1748-717X-7-128-2.jpg

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引用本文的文献

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2
Global adoption of single-shot targeted intraoperative radiotherapy (TARGIT-IORT) for breast cancer-better for patients, better for healthcare systems.全球采用单次靶向术中放射治疗（TARGIT-IORT）治疗乳腺癌——对患者更好，对医疗系统更好。
Front Oncol. 2022 Aug 11;12:786515. doi: 10.3389/fonc.2022.786515. eCollection 2022.
3
Case Report: Can Targeted Intraoperative Radiotherapy in Patients With Breast Cancer and Pacemakers be the New Standard of Care?

本文引用的文献

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Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial.针对乳腺癌的术中放疗与全乳放疗（TARGIT-A 试验）：一项国际性、前瞻性、随机、非劣效性 3 期试验。
Lancet. 2010 Jul 10;376(9735):91-102. doi: 10.1016/S0140-6736(10)60837-9.
2
Effect of radiation therapy on the latest generation of pacemakers and implantable cardioverter defibrillators: A systematic review.放射治疗对最新一代起搏器和植入式心脏复律除颤器的影响：一项系统评价。
J Med Imaging Radiat Oncol. 2010 Feb;54(1):53-61. doi: 10.1111/j.1754-9485.2010.02138.x.
3
病例报告：乳腺癌合并起搏器患者的术中靶向放疗能否成为新的护理标准？
Front Oncol. 2022 Jul 12;12:927174. doi: 10.3389/fonc.2022.927174. eCollection 2022.
4
Targeted Intraoperative Radiotherapy Is a Safe Approach for Patients with Pacemakers: A Case Study and Literature Review.靶向术中放疗对起搏器患者是一种安全的治疗方法：病例研究与文献综述
Case Rep Oncol. 2020 Jul 30;13(2):916-922. doi: 10.1159/000508946. eCollection 2020 May-Aug.
5
Accelerated Partial Breast Irradiation in Clinical Practice.临床实践中的加速部分乳腺照射
Breast Care (Basel). 2015 Aug;10(4):247-52. doi: 10.1159/000437194. Epub 2015 Jul 15.
6
DEGRO/DGK guideline for radiotherapy in patients with cardiac implantable electronic devices.DEGRO/DGK心脏植入式电子设备患者放射治疗指南。
Strahlenther Onkol. 2015 May;191(5):393-404. doi: 10.1007/s00066-015-0817-3. Epub 2015 Mar 5.
Runaway implantable defibrillator--a rare complication of radiation therapy.
失控的植入式除颤器——放射治疗的一种罕见并发症。
Pacing Clin Electrophysiol. 2007 May;30(5):716-8. doi: 10.1111/j.1540-8159.2007.00735.x.
4
Influence of high-energy photon beam irradiation on pacemaker operation.高能光子束照射对起搏器工作的影响。
Phys Med Biol. 2002 Aug 21;47(16):2879-93. doi: 10.1088/0031-9155/47/16/304.
5
Management of radiation oncology patients with implanted cardiac pacemakers: report of AAPM Task Group No. 34. American Association of Physicists in Medicine.植入心脏起搏器的放射肿瘤学患者的管理：美国医学物理学家协会第34任务组报告
Med Phys. 1994 Jan;21(1):85-90. doi: 10.1118/1.597259.
6
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