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斯里兰卡农村地区蓄意自我中毒的流行病学模式变化。

Changing epidemiologic patterns of deliberate self poisoning in a rural district of Sri Lanka.

机构信息

South Asian Clinical Toxicology Research Collaboration, University of Peradeniya, Peradeniya, Sri Lanka.

出版信息

BMC Public Health. 2012 Aug 2;12:593. doi: 10.1186/1471-2458-12-593.

Abstract

BACKGROUND

Acute poisoning is a major public health issue in many parts of the world. The epidemiology and the mortality rate is higher in low and middle income countries, including Sri Lanka. The aim of this study was to provide details about the epidemiology of acute poisoning in a rural Sri Lankan district and to identify the changing patterns and epidemiology of poisoning.

METHODS

A prospective study was conducted from September 2008 to January 2010 in all hospitals with inpatient facilities in Anuradhapura district of North Central Province of Sri Lanka. Acute poisoning data was extracted from patient charts. Selected data were compared to the data collected from a 2005 study in 28 hospitals.

RESULTS

There were 3813 poisoned patients admitted to the hospitals in the Anuradhapura district over 17 months. The annual population incidence was 447 poisoning cases per 100,000 population. The total number of male and female patients was approximately similar, but the age distribution differed by gender. There was a very high incidence of poisoning in females aged 15-19, with an estimated cumulative incidence of 6% over these five years. Although, pesticides are still the most common type of poison, medicinal drug poisonings are now 21% of the total and have increased 1.6 fold since 2005.

CONCLUSIONS

Acute poisoning remains a major public health problem in rural Sri Lanka and pesticide poisoning remains the most important poison. However, cases of medicinal drug poisoning have recently dramatically increased. Youth in these rural communities remain very vulnerable to acute poisoning and the problem is so common that school-based primary prevention programs may be worthwhile.Lalith Senarathna, Shaluka F Jayamanna, Patrick J Kelly, Nick A Buckley,michael J Dibley, Andrew H Dawson. These authors contributed equally to this work.

摘要

背景

急性中毒是世界上许多地区的一个主要公共卫生问题。在包括斯里兰卡在内的中低收入国家,其流行病学和死亡率更高。本研究旨在提供斯里兰卡一个农村地区急性中毒的流行病学详细信息,并确定中毒的变化模式和流行病学。

方法

2008 年 9 月至 2010 年 1 月,在斯里兰卡中北部省阿努拉德普勒区所有具有住院设施的医院进行了一项前瞻性研究。从患者病历中提取急性中毒数据。将选定的数据与 2005 年 28 家医院收集的数据进行比较。

结果

在 17 个月内,阿努拉德普勒区的医院共收治了 3813 名中毒患者。年人口发病率为每 10 万人中有 447 例中毒病例。男女患者人数大致相同,但性别分布不同。15-19 岁女性中毒发生率极高,五年累积发病率估计为 6%。尽管农药仍然是最常见的中毒类型,但药物中毒现在占总数的 21%,自 2005 年以来增加了 1.6 倍。

结论

急性中毒仍然是斯里兰卡农村地区的一个主要公共卫生问题,农药中毒仍然是最重要的中毒类型。然而,最近药物中毒的病例急剧增加。这些农村社区的年轻人仍然非常容易受到急性中毒的影响,而且这个问题非常普遍,因此基于学校的初级预防方案可能是值得的。Lalith Senarathna、Shaluka F Jayamanna、Patrick J Kelly、Nick A Buckley、michael J Dibley、Andrew H Dawson。这几位作者对此项工作贡献均等。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2644/3458971/992b825272ca/1471-2458-12-593-1.jpg

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