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斯里兰卡农村地区儿童急性中毒的模式与结局

Patterns and outcome of acute poisoning among children in rural Sri Lanka.

作者信息

Dayasiri M B K C, Jayamanne S F, Jayasinghe C Y

机构信息

Paediatrics, University Pediatrics unit, Lady Ridgeway Hospital for Children, Colombo, Sri Lanka.

Clinical Medicine, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.

出版信息

BMC Pediatr. 2018 Aug 18;18(1):274. doi: 10.1186/s12887-018-1246-0.

Abstract

BACKGROUND

The burden of poisoning among children is largely underexplored in rural Sri Lanka. This study describes the patterns of demographic characteristics, poison related factors, clinical management and outcome following acute poisoning among children (9 months- 12 years) in rural Sri Lanka.

METHOD

This hospital based multi-center study included Anuradhapura Teaching hospital, Polonnaruwa District General hospital, and 34 regional hospitals within Regional Director of Health Services in North Central province of Sri Lanka. The study assessed clinical profiles, poison related factors, clinical management, complications, harmful first aid practices, reasons for delayed management, complications and outcomes following acute poisoning over 7 years.

RESULTS

Among 1621 children with acute poisoning, the majority were in preschool age group. Household chemicals were accountable for 489 acute poisonings (30.2%). The most common poison was kerosene oil, followed by paracetamol. Most events occurred within their own domestic premises. Potentially harmful first aid measures were practiced by approximately one third of care givers. Reasons for delayed presentation at emergency center included lack of concern by family members regarding the urgency of the situation and lack of knowledge regarding possible complications. Complications were observed in 12.5% and the most common complication was chemical pneumonitis.

CONCLUSIONS

Children with acute poisoing in rural Sri Lanka were predominantly preschoolers. They are poisonined mostly within their own housing premises. Kerosene oil, in addition to being the most common poison, had additional risks of aspiration pneumonia following potentially hazadrous first aid measures practised by the care givers. Complications though rare were potentially preventable by community education and awareness on timely attention to seek medical care, and avoidance of harmful first aid practices.

摘要

背景

在斯里兰卡农村地区,儿童中毒负担在很大程度上未得到充分研究。本研究描述了斯里兰卡农村地区9个月至12岁儿童急性中毒后的人口统计学特征、中毒相关因素、临床管理及结局模式。

方法

这项基于医院的多中心研究纳入了阿努拉德普勒教学医院、波隆纳鲁沃区总医院以及斯里兰卡中北部省卫生服务区域主任管辖下的34家地区医院。该研究评估了7年间急性中毒后的临床特征、中毒相关因素、临床管理、并发症、有害急救措施、延迟处理的原因、并发症及结局。

结果

在1621例急性中毒儿童中,大多数处于学龄前年龄组。家用化学品导致了489例急性中毒(30.2%)。最常见的毒物是煤油,其次是对乙酰氨基酚。大多数中毒事件发生在他们自己家中。约三分之一的照顾者采取了潜在有害的急救措施。延迟到急诊中心就诊的原因包括家庭成员对情况紧迫性缺乏关注以及对可能并发症缺乏了解。观察到12.5%的患儿出现并发症,最常见的并发症是化学性肺炎。

结论

斯里兰卡农村地区急性中毒儿童主要是学龄前儿童。他们大多在自己家中中毒。煤油除了是最常见的毒物外,在照顾者采取潜在危险的急救措施后还存在吸入性肺炎的额外风险。尽管并发症罕见,但通过社区教育以及提高对及时就医的关注和避免有害急救措施的认识,有可能预防并发症。

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