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Antistaphylococcal activity of pentamidine.喷他脒的抗葡萄球菌活性。
Antimicrob Agents Chemother. 1990 Sep;34(9):1795-6. doi: 10.1128/AAC.34.9.1795.
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本文引用的文献

1
THE EFFECT OF PROPAMIDINE ON BACTERIAL GROWTH.双脒苯脲对细菌生长的影响。
Science. 1943 Sep 3;98(2540):224. doi: 10.1126/science.98.2540.224.
2
The Effect of Aromatic Diamidines on Bacterial Growth: II. The Antagonism of Nucleic Acids and Polyamines.芳香二脒对细菌生长的影响：II. 核酸与多胺的拮抗作用
J Bacteriol. 1948 Jan;55(1):33-41.
3
The Effect of Aromatic Diamidines on Bacterial Growth: I. The Mechanism of Action.芳香二脒对细菌生长的影响：I. 作用机制
J Bacteriol. 1948 Jan;55(1):27-31.
4
The effect of isoniazid, carbutamide, propamidine and pentamidine on the transminases and growth of Escherichia coli, strain 15, mutant M2.异烟肼、甲糖宁、丙脒腙和戊烷脒对大肠杆菌15株突变体M2转氨酶及生长的影响
Biochim Biophys Acta. 1961 Jan 1;46:143-51. doi: 10.1016/0006-3002(61)90657-6.
5
Actions of pentamidine on the metabolism of Staphylococcus aureus.喷他脒对金黄色葡萄球菌代谢的作用。
Biochim Biophys Acta. 1967 Oct 2;144(2):467-70. doi: 10.1016/0005-2760(67)90178-6.
6
Use of a new bioassay to study pentamidine pharmacokinetics.使用一种新的生物测定法来研究喷他脒的药代动力学。
J Infect Dis. 1985 Oct;152(4):750-4. doi: 10.1093/infdis/152.4.750.
7
Pentamidine: a review.喷他脒：综述
Rev Infect Dis. 1985 Sep-Oct;7(5):625-34. doi: 10.1093/clinids/7.5.625.
8
Stability of pentamidine isethionate in 5% dextrose and 0.9% sodium chloride injections.喷他脒异硫氰酸盐在5%葡萄糖注射液和0.9%氯化钠注射液中的稳定性。
Am J Hosp Pharm. 1986 Jun;43(6):1486-8.
9
Use of a specific and sensitive assay to determine pentamidine pharmacokinetics in patients with AIDS.使用特定且灵敏的检测方法来测定艾滋病患者中喷他脒的药代动力学。
J Infect Dis. 1986 Dec;154(6):923-9. doi: 10.1093/infdis/154.6.923.
10
Interaction of hyperthermia and pentamidine in HeLa S-3 cells.高温与喷他脒在海拉S-3细胞中的相互作用。
Radiat Res. 1988 Nov;116(2):320-6.

喷他脒的抗葡萄球菌活性。

Antistaphylococcal activity of pentamidine.

作者信息

Libman M D, Miller M A, Richards G K

机构信息

McGill University, Montreal General Hospital, Quebec, Canada.

出版信息

Antimicrob Agents Chemother. 1990 Sep;34(9):1795-6. doi: 10.1128/AAC.34.9.1795.

DOI:10.1128/AAC.34.9.1795
PMID:2285292
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC171928/
Abstract

Pentamidine isethionate was bacteriostatic against Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Streptococcus sanguis, Micrococcus sp., and Candida albicans. S. aureus was inhibited by concentrations of 16 to 64 micrograms/ml and killed by 64 to greater than or equal to 128 micrograms/ml. Staphylococcal killing was consistently greater in the presence of cations and was unaffected by methicillin resistance.

摘要

乙磺半胱氨酸对金黄色葡萄球菌、表皮葡萄球菌、化脓性链球菌、血链球菌、微球菌属和白色念珠菌具有抑菌作用。金黄色葡萄球菌在浓度为16至64微克/毫升时受到抑制，在64至大于或等于128微克/毫升时被杀死。在有阳离子存在的情况下，葡萄球菌的杀灭作用始终更强，且不受耐甲氧西林性的影响。