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孕32至36周新生儿的肾功能:排泄钠分数的作用

[Kidney function in the newborn infant of 32 to 36 weeks gestation: the usefulness of the excreted sodium fraction].

作者信息

Escobedo-Chávez E, Carvallo-Herrada R, Thompson-Chagoyan O, Ortega-Guzmán S

机构信息

Departamento de Pediatría, Hospital General Dr. Manuel Gea González, México, D.F.

出版信息

Bol Med Hosp Infant Mex. 1990 Nov;47(11):756-9.

PMID:2285463
Abstract

A total of 20 healthy premature newborns, with a gestational age between 32 and 36 weeks were studied for a year. The objective of the study was to determine the utility of the excreted sodium excretion fraction test (FENa) as a parameter used to evaluate renal function in this type of patients, using comparatively the excretion of creatinine. Of the patients studied, 12 were females and the rest males; the medium gestational age was 35.1 weeks (ranging from 32 to 36 weeks); their average weight at birth was 1,943 g (ranging from 1,372 to 2,626 g); serum creatinine varied from 0.3 to 1.2 mg/dL; urinary sodium was measured at 5.37 and 38 mEg/L; the excretion of creatinine was measured at 8.26 +/- 5.18 mL/min/1.73 m2. The FENa varied between 0.1 and 1.71% (x = 0.78 +/- 0.48). The results obtained showed that the FENa is a useful parameter to evaluate renal function in premature newborns with a gestational age between 32 and 36 weeks.

摘要

对20名胎龄在32至36周之间的健康早产新生儿进行了为期一年的研究。该研究的目的是通过比较肌酐排泄情况,确定尿钠排泄分数试验(FENa)作为评估这类患者肾功能的参数的效用。在研究的患者中,12名是女性,其余为男性;平均胎龄为35.1周(范围从32至36周);他们出生时的平均体重为1943克(范围从1372至2626克);血清肌酐在0.3至1.2毫克/分升之间;尿钠测量值为5.37至38毫当量/升;肌酐排泄量测量值为8.26±5.18毫升/分钟/1.73平方米。FENa在0.1%至1.71%之间变化(x = 0.78±0.48)。所得结果表明,FENa是评估胎龄在32至36周之间的早产新生儿肾功能的有用参数。

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