I2 促进了通过无金属 sp3 C-H 功能化的一锅法合成 2-酰基苯并噻唑的多米诺氧化环化反应。
I2 promoted domino oxidative cyclization for one-pot synthesis of 2-acylbenzothiazoles via metal-free sp3 C-H functionalization.
机构信息
Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, 430079, P. R. China.
出版信息
Chem Commun (Camb). 2012 Sep 18;48(72):9086-8. doi: 10.1039/c2cc34561g. Epub 2012 Aug 2.
PMID:22854885
Abstract
An I(2) promoted domino protocol was developed to construct 2-acylbenzothiazoles from simple and readily available aromatic ketones/unsaturated methyl ketones and o-aminobenzenethiols. The reaction proceeded smoothly under metal-free and peroxide-free conditions.
摘要
开发了一种 I(2)促进的级联反应来构建 2-酰基苯并噻唑，该反应原料简单易得，包括芳香酮/不饱和甲基酮和邻氨基苯硫酚。该反应在无金属和无过氧化物条件下顺利进行。
Zotero 插件