Sparenborg S, Gabriel M
Department of Psychology, University of Illinois, Urbana 61801.
Behav Neurosci. 1990 Dec;104(6):919-33. doi: 10.1037//0735-7044.104.6.919.
Neuronal activity in cingulate cortex was recorded during discriminative active avoidance conditioning of rabbits. In one subpopulation of neurons, brief (200 and 500 ms) conditional stimuli (CSs) elicited greater average cingulate cortical training-induced neuronal discharges during conditioned response acquisition than did a long (5,000 ms) CS, and the amount of neuronal discrimination between CS+ and CS- was greater in response to the brief CSs than to the long CS. Neurons in a different subpopulation did not encode CS duration per se but were sensitive to the novelty of the CS duration. Medial dorsal and anteroventral thalamic neurons were suppressed by novel CS durations that activated novelty-sensitive neurons in related cingulate cortical areas. These results are discussed in relation to a theoretical model of the neural mediation of avoidance conditioning.
在兔的辨别性主动回避条件反射过程中，记录了扣带回皮层的神经元活动。在一个神经元亚群中，与长时程（5000毫秒）条件刺激（CS）相比，短暂（200和500毫秒）CS在条件反应习得期间引发了更大的平均扣带回皮层训练诱导神经元放电，并且CS+和CS-之间的神经元辨别量在对短暂CS的反应中比长时程CS更大。另一个不同亚群中的神经元本身并不编码CS持续时间，但对CS持续时间的新颖性敏感。内侧背侧和前腹侧丘脑神经元被激活相关扣带回皮层区域中新颖性敏感神经元的新颖CS持续时间所抑制。结合回避条件反射的神经介导理论模型对这些结果进行了讨论。
