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[腮腺上皮-肌上皮癌:一种低级别恶性肿瘤?]

[Epithelial-myoepithelial carcinoma of parotid gland: a tumor of low grade malignancy?].

作者信息

Fonte Daniela, Aguas Lúcia Nunes, Alves Lurdes, Sotto-Mayor Carlos, Pinto Gabriela

机构信息

Serviço de Radioterapia, Hospital de São João, Porto, Portugal.

出版信息

Acta Med Port. 2011 Dec;24 Suppl 3:675-80. Epub 2011 Dec 31.

Abstract

Epithelial-myoepithelial carcinoma (EMC) is a rare tumor with predilection for the major salivary glands, mainly the parotid gland. It is a tumor of low grade malignancy, and despite its tendency to local recurrence with low metastatic potential, rare cases of EMC may have an aggressive behavior with distant metastasis. Treatment consists primarily of complete surgical resection whenever possible followed by radiotherapy (RT) in an attempt to prevent local recurrence. The authors describe two cases of patients with EMC from the parotid gland. Despite treatment and good local response both later developed pulmonary metastases, and also later cerebral metastization. In the sequence of these clinical cases, a literature review is made.

摘要

上皮-肌上皮癌(EMC)是一种罕见肿瘤,好发于大唾液腺,主要是腮腺。它是一种低度恶性肿瘤,尽管其有局部复发倾向且转移潜能低,但罕见的EMC病例可能具有侵袭性行为并发生远处转移。治疗主要包括尽可能进行完整的手术切除,随后进行放疗(RT),以试图预防局部复发。作者描述了两例来自腮腺的EMC患者。尽管接受了治疗且局部反应良好,但两人后来均发生了肺转移,随后还出现了脑转移。在这些临床病例之后,进行了文献综述。

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