Hovette P, Touze J E, Laroche R
Service de Santé des Armées.
Bull Soc Pathol Exot. 1990;83(4):479-86.
Pulmonary edema is a classic and severe manifestation of falciparum malaria. To evaluate the predictive factors of this severe complication, we studied epidemiological, clinical and biological data of 136 patients with acute malaria. Two groups were individualized according to the presence (group I = 53 patients) or the absence (group II = 83 patients) of pulmonary manifestations. Pulmonary signs incidence was not correlated with impairement consciousness, creatinemia, hypoglycemia, and coagulation abnormalities. However, age, tobacco abused, delay in starting treatment, oliguria, decreased protidemia were significantly increased. These factors, associated with severe malaria, expose to a more important risk of pulmonary edema, often induced by reanimation management.
肺水肿是恶性疟的一种典型且严重的表现。为评估这种严重并发症的预测因素，我们研究了136例急性疟疾患者的流行病学、临床和生物学数据。根据有无肺部表现将患者分为两组（I组 = 53例患者；II组 = 83例患者）。肺部体征的发生率与意识障碍、肌酐血症、低血糖及凝血异常无关。然而，年龄、长期吸烟、开始治疗延迟、少尿、血浆蛋白降低则显著增加。这些与重症疟疾相关的因素使发生肺水肿的风险更高，而肺水肿常由复苏治疗引发。
